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Indian Pediatr ; 51(9): 730-2, 2014 Sep.
Article in English | MEDLINE | ID: mdl-25228607

ABSTRACT

OBJECTIVE: To describe the clinical profile, immunological status and outcome of BCG disease in infants. METHODS: All infants with a diagnosis of BCG disease in a period of 17 months were followed up. RESULTS: Among 25 infants with BCG disease; 19 had local/regional involvement and 6 had suspected or confirmed distant/disseminated disease, Mean (range) age of presentation was 3.6 (1.5-9) months. Two of 6 infants with disseminated disease required second-line anti-tubercular treatment. One infant with confirmed disseminated disease had INFg R1 receptor deficiency. There was no mortality. CONCLUSION: Most infants with BCG- related disease have local or regional disease.


Subject(s)
BCG Vaccine/adverse effects , Mycobacterium bovis , Tuberculosis , Antitubercular Agents/therapeutic use , Humans , Infant , Lymphatic Diseases , Tuberculosis/diagnosis , Tuberculosis/drug therapy , Tuberculosis/microbiology , Tuberculosis/physiopathology
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