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1.
Appl Opt ; 34(11): 1783-7, 1995 Apr 10.
Article in English | MEDLINE | ID: mdl-21037723

ABSTRACT

A new assembly method is described for easy construction of optical modules consisting of guide frames, spacer frames, and a housing frame. This method is used to assemble a two-dimensional optical-fiber collimator and a digital discrete correlator, which are fundamental parts of free-space optical computing systems. We show that a multistage optical system can be constructed simply by stacking of several optical functional blocks. Moreover, these compact modules do not need a conventional optical bench, they are compact, and assembly time is reduced. We demonstrated by experiment that the accuracy of optical modules assembled with this method is within the specifications of the optical system.

2.
Jpn J Pharmacol ; 65(2): 175-7, 1994 Jun.
Article in English | MEDLINE | ID: mdl-7967231

ABSTRACT

S-312, S-312-d, but not S-312-l, L-type calcium channel antagonists, showed anticonvulsant effects on the audiogenic tonic convulsions in DBA/2 mice; and their ED50 values were 18.4 (12.8-27.1) mg/kg, p.o. and 15.0 (10.2-23.7) mg/kg, p.o., respectively, while that of flunarizine was 34.0 (26.0-44.8) mg/kg, p.o. Although moderate anticonvulsant effects of S-312-d in higher doses were observed against the clonic convulsions induced by pentylenetetrazole (85 mg/kg, s.c.) or bemegride (40 mg/kg, s.c.), no effects were observed in convulsions induced by N-methyl-D-aspartate, picrotoxin, or electroshock in Slc:ddY mice. S-312-d may be useful in the therapy of certain types of human epilepsy.


Subject(s)
Anticonvulsants/therapeutic use , Calcium Channel Blockers/therapeutic use , Dihydropyridines/therapeutic use , Seizures/drug therapy , Administration, Oral , Animals , Anticonvulsants/administration & dosage , Bemegride/administration & dosage , Bemegride/toxicity , Calcium Channel Blockers/administration & dosage , Dihydropyridines/administration & dosage , Disease Models, Animal , Electroshock , Female , Injections, Subcutaneous , Male , Mice , Mice, Inbred DBA , N-Methylaspartate/administration & dosage , N-Methylaspartate/toxicity , Pentylenetetrazole/administration & dosage , Pentylenetetrazole/toxicity , Picrotoxin/administration & dosage , Picrotoxin/toxicity , Seizures/chemically induced
3.
Opt Lett ; 18(11): 864, 1993 Jun 01.
Article in English | MEDLINE | ID: mdl-19802297
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