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1.
Synthesis of 7-substituted tetracycline derivatives.
Koza, D J.
Org Lett ; 2(6): 815-7, 2000 Mar 23.
Article in English | MEDLINE | ID: mdl-10754684

ABSTRACT

[formula: see text] The synthesis of 7-substituted tetracycline derivatives has been accomplished in high yield from 7-halotetracyclines by modified Suzuki and Stille coupling protocols. These novel derivatives may serve as a new class of tetracycline antibiotics effective against multi-antibiotic-resistant bacteria.


Subject(s)
Anti-Bacterial Agents/chemical synthesis , Tetracyclines/chemical synthesis , Indicators and Reagents , Models, Molecular , Molecular Structure
2.
Intrauterine decompression of megalocystis during the second trimester of pregnancy.
Gadziala, N A; Kawada, C Y; Doherty, F J; Koza, D J.
Am J Obstet Gynecol ; 144(3): 355-6, 1982 Oct 01.
Article in English | MEDLINE | ID: mdl-7124848

Subject(s)
Fetal Diseases/therapy , Urinary Bladder Diseases/therapy , Dilatation, Pathologic/diagnosis , Female , Fetal Diseases/diagnosis , Humans , Infant, Newborn , Male , Pregnancy , Pregnancy Trimester, Second , Prune Belly Syndrome/complications , Punctures , Ultrasonography , Urinary Bladder Diseases/diagnosis , Urinary Bladder Diseases/etiology
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