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1.
Klin Khir ; (12): 76-8, 2013 Dec.
Article in Ukrainian | MEDLINE | ID: mdl-24502019

ABSTRACT

In experimental polytrauma conditions in the blood serum the immune complexes are accumulating. The dynamics of their contents is a wave-like, the periods of increase are determined--in 3 and 21 days and reduction--in 7-14 and 28 days. Accordingly, the IgA and IgG contents are changing with characteristic significant reduction in 14 days of posttraumatic period. The IgM content reaches maximum in 1-3 days with further reduction lower than norm till the end of experiment.


Subject(s)
Antigen-Antibody Complex/blood , Immunoglobulin A/blood , Immunoglobulin G/blood , Immunoglobulin M/blood , Multiple Trauma/blood , Animals , Animals, Outbred Strains , Kinetics , Male , Multiple Trauma/immunology , Multiple Trauma/pathology , Periodicity , Rats , Time Factors
2.
Klin Khir ; (9): 70-2, 2013 Sep.
Article in Ukrainian | MEDLINE | ID: mdl-24501935

ABSTRACT

The changes in the late apoptosis intensity in lymphocytes, obtained from various organs under polytrauma impact, were studied in experiment. In laboratory animals of a control group the late apoptosis intensity appeared essentially bigger in pulmonary lymphocytes, comparing with those from the heart and the liver. Nonsignificant changes of intensity prolong 2 h - 3 days with essential increase in 7 days, decrease--on the 14-21th days and repeated increase--on the 28th day were characteristic in the polytrauma dynamics for late apoptosis in the lymphocytes, obtained from the lungs, the heart and the liver. It is more characteristic for pulmonary lymphocytes, significantly less--for those from the heart and even lesser--from the liver.


Subject(s)
Apoptosis , Liver/pathology , Lung/pathology , Lymphocytes/pathology , Multiple Trauma/pathology , Myocardium/pathology , Animals , Disease Models, Animal , Male , Rats , Time Factors
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