ABSTRACT
A form of spondylocostal dysostosis, marked by multiple vertebral clefts, costal bifurcation, and fusion was observed in identical male twins whose parents were first cousins. The lack of previous anomalies in the family, the high degree of parental inbreeding and the absence of deformities in a 3-year-old brother indicated an autosomal recessive mode of inheritance.
Subject(s)
Diseases in Twins/genetics , Dysostoses/genetics , Ribs/abnormalities , Spine/abnormalities , Twins, Monozygotic , Dysostoses/diagnostic imaging , Genes, Recessive , Humans , Infant, Newborn , Male , Radiography , Ribs/diagnostic imaging , Spine/diagnostic imagingABSTRACT
Babies of 17 HBsAg positive mothers were passively and actively immunized with HBIG and HBV vaccine. Seven infants born from HBsAg (+) mothers were not immunized with their families decisions and used as control group. 24 infants were followed for 12-18 months. 76.4% of immunized babies were anti-HBs positive at 12 months. None of the babies who were not immunized were HBsAg positive at 12 months.
