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Bull Exp Biol Med ; 148(3): 474-7, 2009 Sep.
Article in English, Russian | MEDLINE | ID: mdl-20396716

ABSTRACT

In patients with ankylosing spondyloarthritis, artrofoon produced a more potent antiinflammatory effect than nonsteroidal antiinflammatory drugs. The study demonstrated a positive effect of artrofoon on clinical and laboratory parameters, good tolerability of the preparation, and the absence of negative effects on the hepatic and renal functions. Being added to complex therapy, artrofoon led to a decrease in the dose of nonsteroidal antiinflammatory drugs.


Subject(s)
Antibodies, Monoclonal/therapeutic use , Spondylitis, Ankylosing/drug therapy , Adult , Antibodies, Monoclonal/adverse effects , Antibodies, Monoclonal/immunology , Female , Humans , Male , Middle Aged , Treatment Outcome , Tumor Necrosis Factor-alpha/immunology
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