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1.
Molecules ; 29(11)2024 May 29.
Article in English | MEDLINE | ID: mdl-38893435

ABSTRACT

This work describes the development of a reusable 2D detector based on radiochromic reaction for radiotherapy dosimetric measurements. It consists of a radiochromic gel dosimeter in a cuboidal plastic container, scanning with a flatbed scanner, and data processing using a dedicated software package. This tool is assessed using the example of the application of the coincidence test of radiation and mechanical isocenters for a medical accelerator. The following were examined: scanning repeatability and image homogeneity, the impact of image processing on data processing in coincidence tests, and irradiation conditions-monitor units per radiation beam and irradiation field are selected. Optimal conditions for carrying out the test are chosen: (i) the multi-leaf collimator gap should preferably be 5 mm for 2D star shot irradiation, (ii) it is recommended to apply ≥2500-≤5000 MU per beam to obtain a strong signal enabling easy data processing, (iii) Mean filter can be applied to the images to improve calculations. An approach to dosimeter reuse with the goal of reducing costs is presented; the number of reuses is related to the MUs per beam, which, in this study, is about 5-57 for 30,000-2500 MU per beam (four fields). The proposed reusable system was successfully applied to the coincidence tests, confirming its suitability as a new potential quality assurance tool in radiotherapy.


Subject(s)
Radiation, Ionizing , Radiometry/methods , Radiometry/instrumentation , Gels/chemistry , Radiotherapy/methods , Radiotherapy Dosage , Radiation Dosimeters , Particle Accelerators
2.
Materials (Basel) ; 17(7)2024 Mar 27.
Article in English | MEDLINE | ID: mdl-38612035

ABSTRACT

This work presents a Fricke-XO-Pluronic F-127 2D radiochromic dosimeter with a flat-bed scanner for 2D reading and a dedicated data processing software package as a tool for performing coincidence testing of the radiation and mechanical isocenter of a medical accelerator. The optimal irradiation parameters were determined as follows: monitor units per beam and multi-leaf collimator gap, which are ≤750-≤2500 MU and 2-5 mm, respectively, for a cuboidal container with dimensions of 12 × 12 × 0.3 cm3. Despite the diffusion of Fe3+ ions occurring during irradiation, 2D reading can be performed at least 3 h after irradiation, without affecting the calculation performance of the coincidence test. The test was successfully performed for various irradiation settings. Overall, the Fricke-XO-Pluronic F-127 dosimeter has proven to be a potential tool for the coincidence testing of medical accelerators.

3.
Materials (Basel) ; 17(6)2024 Mar 11.
Article in English | MEDLINE | ID: mdl-38541437

ABSTRACT

Dynamically evolving radiotherapy instruments require advancements in compatible 3D dosimetry systems. This paper reports on such tools for the coincidence test of the mechanical and radiation isocenter for a medical accelerator as part of the quality assurance in routine radiotherapy practice. Three-dimensional polymer gel dosimeters were used in combination with 3D reading by iterative cone beam computed tomography and 3D data processing using the polyGeVero-CT software package. Different polymer gel dosimeters were used with the following acronyms: VIP, PAGAT, MAGIC, and NIPAM. The same scheme was used for each dosimeter: (i) irradiation sensitivity test for the iterative cone beam computed tomography reading to determine the appropriate monitor unit for irradiation, and (ii) verification of the chosen irradiation conditions by a star-shot 2D irradiation of each 3D dosimeter in the direction of performing the test. This work concludes with the optimum monitor unit per beam for each selected 3D dosimeter, delivers schemes for quick and easy determination of the radiation isocenter and performing the coincidence test.

4.
Int J Mol Sci ; 25(5)2024 Mar 02.
Article in English | MEDLINE | ID: mdl-38474163

ABSTRACT

This work presents an ecological, flexible 2D radiochromic dosimeter for measuring ionizing radiation in the kilogray dose range. Cotton woven fabric made of cellulose was volume-modified with nitrotetrazolium blue chloride as a radiation-sensitive compound. Its features include a color change during exposure from yellowish to purple-brown and flexibility that allows it to adapt to various shapes. It was found that (i) the dose response is up to ~80 kGy, (ii) it is independent of the dose rate for 1.1-73.1 kGy/min, (iii) it can be measured in 2D using a flatbed scanner, (iv) the acquired images can be filtered using a mean filter, which improves its dose resolution, (v) the dose resolution is -0.07 to -0.4 kGy for ~0.6 to ~75.7 kGy for filtered images, and (vi) two linear dose subranges can be distinguished: ~0.6 to ~7.6 kGy and ~9.9 to ~62.0 kGy. The dosimeter combined with flatbed scanner reading and data processing using dedicated software packages constitutes a comprehensive system for measuring dose distributions for objects with complex shapes.


Subject(s)
Radiation Dosimeters , Radiation, Ionizing , Cellulose , Radiometry/methods
5.
Materials (Basel) ; 16(20)2023 Oct 14.
Article in English | MEDLINE | ID: mdl-37895673

ABSTRACT

This work presents the results of paper laser processing. It begins with the selection and examination of the processing parameters, then an examination of the properties of the modified papers and examples of applications of the developed modification method. The properties of laser-modified paper were studied using reflectance spectrophotometry to examine the colour aspects of the modified papers, scanning electron microscopy (SEM) and confocal microscopy for a morphological analysis, and Raman spectroscopy to analyse the papers under the influence of laser light. The influence of laser processing on the wettability of paper and the evenness of unprinted and printed paper was also investigated. The knowledge gained on paper surface modification with laser light was used to propose several applications, such as methods of marking, tactile detection, the controlled removal of optical brightener, ink, and metallised coatings from paper packaging, highlighting the design and aesthetics of paper. The developed laser-assisted method shows a promising, ecological approach to the design of many value-added paper products.

6.
Materials (Basel) ; 16(17)2023 Aug 22.
Article in English | MEDLINE | ID: mdl-37687427

ABSTRACT

This work reports on the new chemical dosimeters for UV radiation dose measurements on coral reefs and in seawater. The proposed dosimeters can measure the actual dose of UV radiation, which consists of 95% UVA and 5% UVB radiation, unlike the currently-used radiometers in marine and ocean waters that measure the dose of UVA and UVB radiation separately. The dosimeters are composed of water, poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127) as a gel matrix, and 2,3,5-triphenyltetrazolium chloride (TTC) as a UV radiation-sensitive compound. In the work, the dosimeters were characterised in terms of their response to the dose of UV radiation depending on the TTC concentration and the irradiation and storage conditions of the dosimeters. The stability of the dosimeters over time was also examined. The obtained results indicate that the TTC-Pluronic F-127 dosimeters can be used to measure absorbed doses of UV radiation in the saltwater environment. The developed dosimeters with a concentration of 0.1% TTC can be used up to 5 J/cm2, which predisposes them to UV radiation measurements at a depth of more than 10 m in sea and ocean waters in 10-min intervals during all months throughout the year.

7.
Materials (Basel) ; 16(16)2023 Aug 14.
Article in English | MEDLINE | ID: mdl-37629913

ABSTRACT

This work concerns the new idea of textile printing with a multi-color system using pastes containing compounds sensitive to ultraviolet (UV) radiation. A screen printing method based on a modified CMYK color system was applied to a cotton woven fabric. Aqueous printing pastes were prepared from thickening and crosslinking agents and UV-sensitive compounds: leuco crystal violet (LCV), leuco malachite green (LMG), and 2,3,5-triphenyltetrazolium chloride (TTC) instead of the system's standard process colors: cyan, magenta, and yellow. Depending on the number of printed layers and the type of UV radiation (UVA, UVB, and UVC), the modified textile samples change color after irradiation from white to a wide range of colors (from blue, red, and green to purple, brown, and gray). Based on reflectance measurements, the characteristic parameters of the one-, two-, and three-color-printed samples in relation to absorbed dose were determined, e.g., dose sensitivity, linear and dynamic dose response, and threshold dose. This printing method is a new proposal for UV dosimeters and an alternative standard for textile printing. Furthermore, the developed method can be used for the securing, marking, and creative design of textiles and opens up new possibilities for such stimulus-sensitive reactive printing.

8.
Phys Med ; 104: 23-31, 2022 Dec.
Article in English | MEDLINE | ID: mdl-36356501

ABSTRACT

PURPOSE: A new commercial 2D ionising radiation dosimeter (2Day.QA®) was developed. This work aims to introduce the basic functions of 2Day.QA®. METHODS: The dosimeter is made mainly of a linear polysaccharide consisting of ß(1 â†’ 4) linked d-glucose units and radiation active substances, which make it environmentally friendly. For 2Day.QA® irradiation, radiotherapy ionising radiation sources were used. The analysis of 2Day.QA® was performed using three scanners: Vidar® Red LED Dosimetry Pro Advantage™, Vidar® VXR 12-plus™ and HP Scanjet G3010 flatbed scanner. The stability of 2Day.QA® was tested. Exemplary applications of 2DayQA® for QA studies of accelerator light and radiation field coincidence and brachytherapy source position were carried out. RESULTS: The dosimeter responded to the lowest applied dose of 0.95 Gy and saturated at over 94.9 Gy. The quasi-linear dose response is below 20 Gy. Vidar® Red LED Dosimetry Pro Advantage™ has proven to be superior to other scanners at determining dose effects in 2Day.QA®. The stability of the non-irradiated 2Day.QA® is at least 18 months. After 18 months of storage, the dosimeter reacted to irradiation. In the case of the irradiated samples, a slight color drift related to the absorbed dose was observed. Tests of the use of 2Day.QA® to control the quality of the accelerator light and radiation field coincidence and brachytherapy source position have shown that it can be used for such applications. CONCLUSIONS: The study reveals the potential of 2Day.QA® for 2D radiation dosimetry and concludes with recommendations for the use of the dosimeter for radiotherapy QA tests.


Subject(s)
Radiation Dosimeters , Polysaccharides , Glucose
9.
Materials (Basel) ; 15(19)2022 Sep 30.
Article in English | MEDLINE | ID: mdl-36234149

ABSTRACT

This work presents an approach to the fast determination of a medical accelerator irradiation isocenter as a quality assurance (QA) procedure in radiotherapy. The isocenter determination tool is the tissue equivalent high-resolution 3D polymer gel dosimeter (PABIGnx) in a dedicated container combined with kilovoltage imaging systems and the polyGeVero-CT software package (v. 1.2, GeVero Co., Poland). Two accelerators were employed: Halcyon and TrueBeam (Varian, USA), both equipped with cone beam computed tomography (CBCT) and iterative reconstruction CBCT (iCBCT) algorithms. The scope of this work includes: (i) the examination of factors influencing image quality (reconstruction algorithms and modes), radiation field parameters (dose and multi-leaf collimator (MLC) gaps), fiducial markers, signal averaging for reconstruction algorithms and the scanning time interval between consecutive scans, (ii) the examination of factors influencing the isocenter determination, image processing (signal averaging, background subtraction, image filtering) and (iii) an isocenter determination report using a 2D and 3D approach. An optimized protocol and isocenter determination conditions were found. The time and effort required to determine the isocenter are discussed.

10.
Materials (Basel) ; 15(20)2022 Oct 14.
Article in English | MEDLINE | ID: mdl-36295222

ABSTRACT

This works reports on the effects of treating the surface of Ti6Al4V titanium alloy samples with a laser with a wavelength of 1064 nm, operating in a pulsed and continuous mode. The obtained surfaces with different roughness, complexity and wettability were examined by Raman spectroscopy in order to recognize the presence of titanium oxides on the functionalized surface. The layer of titanium oxides on the surface with the identified rutile phase obtained by laser treatment in the continuous wave mode is a reason for a hydrophobic surface that appeared 50 days after the treatment process. In the case of the surface obtained by the pulsed laser process, only local points at which the Raman bands attributed to the metastable phases anatase and brookite of TiO2 can be identified. In this treatment process, complete surface hydrophilicity was observed during 29 days after the functionalization process (maximal contact angle observed during this time was 68.4 deg). For some functionalization processes of different parameters, the contact angle remained immeasurable until 119 days after the functionalization process. In summary, Raman spectroscopy identifies surface changes of Ti6Al4V after laser processing.

11.
Materials (Basel) ; 15(15)2022 Jul 28.
Article in English | MEDLINE | ID: mdl-35955164

ABSTRACT

Fricke-XO-Pluronic F-127 has recently been proposed as a 3D dosimeter for radiotherapy. It contains the typical ingredients of the Fricke ionizing radiation dosimeter, which are embedded in a physical gel of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127). The main reactions upon irradiation are the conversion of Fe+2 to Fe+3 and the formation of a colored complex with XO ([XO-Fe]+3). The study attempts to optimize the dosimeter in terms of its solution-to-gel transition temperature. In order to lower this temperature, the use of NaCl salt has been proposed. The new composition was characterized in order to obtain information on its thermal performance, storage stability, dose response to irradiation with a medical accelerator emitting different types of radiation, and tissue equivalence. The results obtained show an improvement in the sol-gel transition temperature and dose sensitivity compared to the composition without NaCl and broaden the knowledge of the Fricke-XO-Pluronic F-127.

12.
Int J Mol Sci ; 23(10)2022 May 12.
Article in English | MEDLINE | ID: mdl-35628215

ABSTRACT

Golden and silver-golden chitosan hydrogels and hydrogel-modified textiles of potential biomedical applications are investigated in this work. The hydrogels are formed by reactions of chitosan with HAuCl4·xH2O. For above the critical concentration of chitosan (c*), chitosan-Au hydrogels were prepared. For chitosan concentrations lower than c*, chitosan-Au nano- and microgels were formed. To characterise chitosan-Au structures, sol-gel analysis, UV-Vis spectrophotometry and dynamic light scattering were performed. Au concentration in the hydrogels was determined by the flame atomic absorption spectrophotometry. Colloidal chitosan-Au solutions were used for the modification of fabrics. The Au content in the modified fabrics was quantified by inductively coupled plasma mass spectrometry technique. Scanning electron microscopy with energy dispersion X-ray spectrometer was used to analyse the samples. Reflectance spectrophotometry was applied to examine the colour of the fabrics. The formation of chitosan-Au-Ag hydrogels by the competitive reaction of Au and Ag ions with the chitosan macromolecules is reported.


Subject(s)
Chitosan , Silver , Chitosan/chemistry , Hydrogels/chemistry , Microscopy, Electron, Scanning , Silver/chemistry , Textiles
13.
Materials (Basel) ; 15(7)2022 Mar 23.
Article in English | MEDLINE | ID: mdl-35407702

ABSTRACT

This work reports on radiochromic dosimeters for 1D UV light measurements. The dosimeter is composed of a 25% Pluronic F-127 that forms a physical gel matrix and nitro blue tetrazolium chloride (NBT) as a radiation-sensitive compound. This dosimeter was exposed to UVA, UVB and UVC radiation, and the radiochromic reactions were followed with reflectance spectrophotometry including changes in light reflectance and color coordinates in the CIELAB color system. The exposition of dosimeters to all UV radiation caused color changes from pale yellow to dark violet, and its intensity increased with increasing absorbed dose. The effects of NBT concentration and UV radiation type on the dose-response of the dosimeters were also examined. The results obtained reveal that the dosimeters are the least sensitive to irradiation with UVC and the most sensitive to irradiation with UVB (e.g., dosimeter with 2 g/dm3 of NBT was characterized by the following parameters: the threshold dose 0.1 J/cm2; the dose sensitivity -5.97 ± 0.69 cm2/J; the linear dose range 0.1-2.5 J/cm2; the dynamic dose range was equal to 0.1-3 J/cm2). The results obtained reveal that the NBT-Pluronic F-127 dosimeters can be potentially useful as 1D sensors for artificial UV radiation sources measurements.

14.
Materials (Basel) ; 15(7)2022 Mar 30.
Article in English | MEDLINE | ID: mdl-35407878

ABSTRACT

This work reports on a new TBO-Pluronic F-127 three-dimensional (3D) gel dosimeter for UV light dose distribution measurements. The optimal gel composition was found to be 60 µM Toluidine Blue O (TBO), which acts as a UV-sensitive compound; 5% w/w hydrogen peroxide (H2O2), which is necessary for initiation of TBO photodegradation and 25% w/w poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127), which forms a physical gel matrix. The dosimeter becomes discoloured when exposed to UV radiation and a discolouration is the more intense, the higher the absorbed dose is. The samples after irradiation with UVA, UVB and UVC radiation were measured using UV-Vis spectrophotometry to obtain the basic dose-response characteristic of the dosimeter, including dose sensitivity, linear and dynamic dose range, threshold dose, stability over time and dose-response for fractioned and non-fractioned doses. Additionally, the TBO-Pluronic F-127 gel dosimeter was investigated for spatial stability and the ability to measure the dose distribution of UV radiation. The results obtained indicate that the TBO-Pluronic F-127 dosimeter is a promising UV sensor and 2D/3D UV dosimeter.

15.
Materials (Basel) ; 15(7)2022 Mar 31.
Article in English | MEDLINE | ID: mdl-35407883

ABSTRACT

This work presents the features of the PABIGnx 3D polymer gel dosimeter. It consists of two cross-linkers: poly(ethylene glycol) diacrylate (PEGDA), as one biacrylic component, and N,N'-methylenebisacrylamide (MBA), which is another cross-linker often used in 3D dosimeters. Additionally, it contains oxygen scavenges of copper sulfate pentahydrate and ascorbic acid. All ingredients are embedded in a physical gel matrix of gelatine. Upon irradiation, the biacrylic cross-linking agents (PEGDA and MBA) undergo radical polymerisation and cross-linking, which is manifested by the appearance of the opacity of the intensity related to the absorbed dose. PABIGnx was irradiated with an oncological source of ionising radiation, and analysed by using a nuclear magnetic resonance (0.5 T). The following characteristics were obtained: (i) linear and dynamic dose-response of 0.5 to ~18 Gy and 40 Gy, respectively, (ii) dose sensitivity of 0.071 ± 0.001 Gy-1 s-1, (iii) integral 3D dose distribution for at least 24 days after irradiation, (iv) adequate batch-to-batch reproducibility, (v) dose-response independent of irradiation with 6 MV photons, 15 MV photons, 6 MV photons FFF of 0.0168-0.1094 Gy/s dose rates, and (vi) soft tissue equivalence. The study showed that the features of PABIGnx confirm its suitability for use in 3D radiotherapy dosimetry.

16.
Materials (Basel) ; 15(3)2022 Jan 27.
Article in English | MEDLINE | ID: mdl-35160929

ABSTRACT

This paper presents the results of research on the Fricke-XO-Pluronic F-127 dosimeter. It consists of a Fricke dosimetric solution and xylenol orange (XO), which are embedded in a matrix of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127). Upon irradiation, Fe+2 ions transform into Fe+3, forming a colored complex with XO ([XO-Fe]+3). The color intensity is related to the dose absorbed. The optimal composition, storage conditions, and radiation-induced performance of the Fricke-XO-Pluronic F-127 dosimeter were investigated. The optimal composition was found to be 1 mM FAS, 50 mM sulfuric acid (H2SO4), 0.165 mM XO in 25% Pluronic F-127. The basic features of this dosimeter are discussed, such as dose sensitivity, linear and dynamic dose range, stability before and after irradiation, storage conditions, dose response for irradiation with 6 and 15 MV photons, and batch-to-batch reproducibility. The obtained results showed a certain potential of the Fricke-XO-Pluronic F-127 for radiotherapy dosimetry.

17.
Materials (Basel) ; 14(14)2021 Jul 15.
Article in English | MEDLINE | ID: mdl-34300879

ABSTRACT

This paper aims to explain the phenomenon of laser light trapping (LLT) in a 3D polymer gel dosimeter. A VIC-T polymer gel dosimeter containing 17% N-vinylpyrrolidone, 8% N,N'-methylenebisacrylamide, 12% tert-butyl alcohol, 5% gelatine, 0.02% hydroquinone and 14 mM tetrakis(hydroxymethyl)phosphonium chloride was used in this study. It was exposed to green laser light with a wavelength of 532 nm. A film was recorded during the exposure. After exposure, Raman spectroscopy was used to study the reactions taking place inside the dosimeter. The obtained results were used to explain what the LLT phenomenon is, what are the consequences for the dosimeter in which such a phenomenon occurs, and what dosimeter components play an important role in the occurrence of LLT. In addition, the conditions under which 3D polymer gel dosimeters can be measured using optical computed tomography at short wavelengths of visible laser light are indicated.

18.
Materials (Basel) ; 14(14)2021 Jul 17.
Article in English | MEDLINE | ID: mdl-34300925

ABSTRACT

This work reports a modification of a fibrous cellulose material (paper) by the addition of polyacrylonitrile (PAN) fibres doped with 10,12-pentacosadiynoic acid (PDA). The fibres are sensitive to ultraviolet (UV) light. When the paper containing PAN-PDA is irradiated with UV light it changes colour to blue as a consequence of interaction of the light with PDA. The colour intensity is related to the absorbed dose, content of PAN-PDA fibres in the paper and the wavelength of UV radiation. The features of the paper are summarised after reflectance spectrophotometry and scanning microscopy analyses. All the properties of the modified paper were tested in accordance with adequate ISO standards. Moreover, a unique method for assessing the unevenness of the paper surface and the quality of printing was proposed by using a Python script (RGBreader) for the analysis of RGB colour channels. The modification applied to the paper can serve as a paper security system. The modified paper can act also as a UV radiation indicator.

19.
Materials (Basel) ; 14(12)2021 Jun 21.
Article in English | MEDLINE | ID: mdl-34205722

ABSTRACT

This work reports on the surface-modified woven fabrics for use as UV radiation sensors. The cotton and polyamide fabrics were printed with radiochromic hydrogels using a screen-printing method. The hydrogels used as a printing paste were composed of water, poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127) as a gel matrix and nitro blue tetrazolium chloride as a radiation-sensitive compound. The development of the hydrogels' colour occurs after exposure to UV radiation and its intensity increases with increasing absorbed dose. The features of the NBT-Pluronic F-127 radiochromic hydrogels and the fabrics printed with the hydrogels were examined using UV-Vis and reflectance spectrophotometry as well as scanning electron microscopy (SEM). The effects of NBT concentration and UV radiation type (UVA, UVB, UVC) on dose responses of the hydrogels and printed fabrics were also examined. The results obtained reveal that the fabrics printed with NBT-Pluronic F-127 hydrogels can be potentially useful as UV radiation sensors.

20.
Med Phys ; 47(8): 3600-3613, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32301510

ABSTRACT

PURPOSE: The purpose of this work was to examine the suitability of VIPARnd polymer gel-9.4 T magnetic resonance microimaging system for high spatial resolution dose distribution measurements. METHODS: The VIPARnd samples (3 cm in outside diameter and 12 cm in height) were exposed to ionizing radiation by using a linear accelerator (Varian TrueBeam, USA; 6 MV x-ray beam). In the calibration stage, nine gel dosimeter vials were irradiated in a water phantom homogenously to the doses from 1.5 to 30 Gy in order to obtain R2-dose relation. In the verification stage, two gel dosimeter vials were irradiated in the half beam penumbra area of 10 × 10 cm radiation field using the amount of monitor units appropriate to deliver 20 Gy at the field center. The gels were imaged on a vertical 9.4 T magnetic resonance (MR) microimaging scanner using single slice and multislice (9 slices) multiecho (90 × 7 ms) sequences at the spatial resolutions of 0.2-0.4 × 0.2-0.4 × 3 mm3 and 0.2-0.4 × 0.2-0.4 × 1 mm3 respectively. The gels were subjected to microimaging during the period of two weeks after irradiation. The reference data consisted of the dose profiles measured using the diode dosimetry, radiochromic film, ionization chamber, and the water phantom system. RESULTS: The VIPARnd -9.4 T MR microimaging system was characterized by the dose sensitivity of 0.067 ± 0.002 Gy-1  s-1 at day 3 after irradiation. The dose resolution at 10 Gy (at P = 95%) was equal to 0.42 Gy at day 3 after irradiation using a single slice sequence (0.2 × 0.2 × 3 mm3 ) and 2.0 Gy at day 4 after irradiation using a multislice sequence (0.2 × 0.2 × 1 mm3 ) for one signal acquisition (measurement time: 15 min). These values were improved by ~1.4-fold when using four signal acquisitions in the single slice sequence, and by ~2.78-fold for 12 signal acquisitions in the multislice sequence. Furthermore, decreasing the in-plane resolution from 0.2 × 0.2 mm2 to 0.4 × 0.4 mm2 resulted in a dose resolution of 0.3 Gy and 1 Gy at 10 Gy (at P = 95%) for one signal acquisition in the single slice and multislice sequences respectively (measurement time: 7.5 min). As reveals from the gamma index analysis the dose distributions measured at days 3-4 postirradiation using both VIPARnd verification phantoms agree with the data obtained using a silicon diode, assuming 1 mm/5% criterion. A good interphantom reproducibility of the polymer gel dosimetry was proved by monitoring of two phantoms up to 10 days after irradiation. However, the agreement between the dose distributions measured using the diode and polymer gel started to get worse from day 5 after irradiation. CONCLUSION: The VIPARnd -9.4T MR microimaging system allows to obtain dose resolution of 0.42 Gy at 10 Gy (at P = 95%) for a spatial resolution of 0.2 × 0.2 × 3 mm3 (acquisition time: 15 min). Further studies are required to improve a temporal stability of the gel-derived dose distribution.


Subject(s)
Polymers , Radiometry , Gels , Magnetic Resonance Spectroscopy , Particle Accelerators , Reproducibility of Results
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