ABSTRACT
Biomass-derived C6-furanic compounds have become the cornerstone of sustainable technologies. The key feature of this field of chemistry is the involvement of the natural process only in the first step, i.e., the production of biomass by photosynthesis. Biomass-to-HMF (5-hydroxymethylfurfural) conversion and further transformations are carried out externally with the involvement of processes with poor environmental factors (E-factors) and the generation of chemical wastes. Due to widespread interest, the chemical conversion of biomass to furanic platform chemicals and related transformations are thoroughly studied and well-reviewed in the current literature. In contrast, a novel opportunity is based on an alternative approach to consider the synthesis of C6-furanics inside living cells using natural metabolism, as well as further transformations to a variety of functionalized products. In the present article, we review naturally occurring substances containing C6-furanic cores and focus on the diversity of C6-furanic derivatives, occurrence, properties and synthesis. From the practical point of view, organic synthesis involving natural metabolism is advantageous in terms of sustainability (sunlight-driven as the only energy source) and green nature (no eco-persisted chemical wastes).
Subject(s)
Photosynthesis , Biomass , Chemistry Techniques, SyntheticABSTRACT
An atom-economic ring construction approach to the synthesis of α-(hetero)arylfurans based on renewable furanic platform chemicals has been developed. Corresponding compounds have been prepared in good to excellent yields via [2+2+2] and [4+2] cycloaddition reactions using metal-catalyzed or photoredox protocols. Easily available HMF-based 2-hydroxymethyl-5-ethynylfuran and 2-hydroxymethyl-5-cyanofuran were used as starting materials. A synthetic route with an improved carbon economy factor has been implemented to achieve sustainability aim. The possible application of arylfurans as molecular conductors has been investigated by DFT calculations, which revealed excellent charge transfer properties. As a future perspective, integration of biomass processing strategy into manufacturing of molecular electronics was pointed out to achieve the aim of sustainability.
ABSTRACT
Visual search (VS) for multiple targets is especially error prone. One of these errors is called subsequent search misses (SSM) and represents a decrease in accuracy at detecting a second target after a first target has been found. One of the possible explanations of SSM errors is working memory (WM) resource depletion. Three experiments investigated the role of WM in SSM errors using a dual task paradigm. The first experiment investigated the role of object WM using a classical color change detection task. In the second and the third experiments, a modified change detection task was applied, using shape as the relevant feature. The results of our study revealed no effect of additional WM task on second target detection in dual-target VS. To this end, SSM errors are not related to WM resource depletion. On the contrary, WM task performance was violated by dual-target VS as compared to single-target VS, when the targets in VS task were defined by the same feature used in the WM task.
