ABSTRACT
In the present work influence of perlite sand has been studied on a skin of Sprague-Dawley male rat (300-350 g). The biopsy of intact rat skin has been used as control. Contact of the perlite sand with animals' skin causes the reaction of an inflammation amplifying with increase of duration of the influence of substance. Therefore, despite an inert chemical compound, long contact with perlite sand in conditions of production can promote development of skin diseases. From the result of this investigation it is concluded that perlite sand causes irritating action on the skin and it is necessary to apply additional protective means to workers contacting to this substance.
Subject(s)
Aluminum Oxide/toxicity , Dermatitis, Contact/etiology , Dermatitis, Contact/pathology , Silicon Dioxide/toxicity , Skin/drug effects , Skin/pathology , Animals , Male , Occupational Exposure/adverse effects , Rats , Rats, Sprague-DawleyABSTRACT
The article is dedicated to the topical problem of allergic diseases in various population groups of a large industrial region of Moscow suburb, and presents a brief review of present-day epidemiological data on allergic pathology prevalence as well as authors' own data on the morbidity of bronchial asthma, allergic dermatoses, and allergic rhinitis. The paper also contains the results of an analysis of allergic pathology dynamics within 5 to 10 years, and a retrospective analysis of allergic pathology structure in adolescents. The researchers undertook a multifactor analysis of population habitat in the town Mitishchy, based upon ecological and hygienic data concerning atmospheric air and water composition. The study points to the role played by industrial environment in the appearance of allergic skin diseases. Complex measures on allergic disease prevention are considered, and an effective pathogenically grounded method of ozonotherapy is suggested as one of prospective non-drug means of treatment.
Subject(s)
Environmental Pollution/adverse effects , Hypersensitivity/epidemiology , Adolescent , Adult , Age Factors , Asthma/epidemiology , Asthma/prevention & control , Child , Child, Preschool , Dermatitis, Atopic/epidemiology , Dermatitis, Atopic/prevention & control , Dermatitis, Occupational/epidemiology , Dermatitis, Occupational/prevention & control , Female , Humans , Hypersensitivity/prevention & control , Hypersensitivity/therapy , Industry , Infant , Infant, Newborn , Male , Moscow , Ozone/therapeutic use , Prevalence , Prospective Studies , Retrospective Studies , Rhinitis, Allergic, Perennial/epidemiology , Rhinitis, Allergic, Perennial/prevention & control , Risk FactorsABSTRACT
It is shown that gauze turunda tamponade of the middle ear postoperative cavities provokes bacterial contamination and formation of the infection focus. Inflatable latex tampon and technique of tamponade of the postoperative middle ear cavities after hearing-preserving sanation operations on the temporal bone were designed and tested. They proved superior to the gauze turundas and allow to avoid bacterial contamination. Microscopic and histological studies confirmed that removal of the latex tampon is safe for the postoperative wound surface making postoperative relapse less probable.
