ABSTRACT
A case of chiasmal neuritis with bilateral, asymmetric optic nerve involvement is presented. Association with recent Epstein-Barr virus infection is suggested. The clinical picture, possible aetiological factors, and causative relation to Epstein-Barr virus are presented.
Subject(s)
Epstein-Barr Virus Infections , Eye Infections, Viral , Optic Chiasm/pathology , Optic Neuritis/virology , Antibodies, Viral/analysis , Child , Epstein-Barr Virus Infections/diagnostic imaging , Epstein-Barr Virus Infections/etiology , Epstein-Barr Virus Infections/pathology , Eye Infections, Viral/diagnostic imaging , Eye Infections, Viral/etiology , Eye Infections, Viral/pathology , Female , Herpesvirus 4, Human/immunology , Humans , Immunoglobulin G/analysis , Immunoglobulin M/analysis , Optic Chiasm/diagnostic imaging , Optic Neuritis/diagnostic imaging , Optic Neuritis/pathology , Tomography, X-Ray ComputedABSTRACT
The coexistence of optic nerve head drusen and pseudotumor cerebri is a potential clinical problem since diagnosing only one of two clinical abnormalities in a patient may delay or prevent the appropriate treatment. To the best of our knowledge, only four cases of such coexistence have been described. We report three cases diagnosed as having both optic nerve head drusen and pseudotumor cerebri and propose possible explanations. The report draws attention to the need for awareness of this potential coexistence in order to assure proper treatment.
Subject(s)
Optic Disk Drusen/complications , Pseudotumor Cerebri/complications , Adult , Female , Fundus Oculi , Humans , Male , Middle Aged , Optic Disk/pathology , Optic Disk Drusen/diagnosis , Pseudotumor Cerebri/diagnosisABSTRACT
The present report describes an iritis-like reaction found in 13 patients treated with recombinant human erythropoietin (Eprex), a drug given to hemodialysis patients for their chronic anemia. Among 120 patients being treated by hemodialysis in two centers affiliated with our medical center, ten out of 30 Eprex-treated patients but none of 90 not being treated with Eprex developed this reaction. The observations described support a causal relation between Eprex treatment and the iritis-like reaction. Further investigative effort is needed to establish the mechanism.
