ABSTRACT
In the complex of treatment of purulent-septic diseases leukinferon at a dose of 300 IU/kg was used according to the following scheme: 3 injections with the 48 h interval between injections. The effect of leukinferon mainly on the function of neutrophil granulocytes and subpopulation of T-lymphocytes was established. Together with clinico-laboratory data indicative of the effectiveness of treatment, normalization of interferon status and decrease in the level of a circulating factor of tumour necrosis in seriously ill patients was observed.
Subject(s)
Adjuvants, Immunologic/therapeutic use , Cytokines/therapeutic use , Focal Infection/therapy , Interferon Type I/therapeutic use , Sepsis/therapy , Wound Infection/therapy , Combined Modality Therapy , Drug Combinations , Focal Infection/immunology , Humans , Sepsis/immunology , Wound Infection/immunologyABSTRACT
The pathogenetic substantiation and technique of intrapleural sorption detoxication (IPSD) based on the use of high-dispersed silicone dioxide (trade mark "AEROSIL") are presented. Use of IPSD in the complex of treatment of 25 children with complicated forms of acute destructive pneumonia permitted to shorten the duration of intoxication syndrome, sanation of suppurative foci, stay of the patients at a hospital.