[Action of aminazine and tisercin in a changed functional state of the body]. / Deistvie aminazina i tizertsina v usloviiakh izmenennogo funkstional'nogo sostoianiia organizma.

Experiments with rats evidenced that the pain-allaying and hypothermal action of chlorpromazine and tisercin (5 and 1 mg/kg) remains intact with an upset homeostasis against the background of a phlogogenic mixture and inflammation effect, though it becomes less potent. These drugs increase the higher permeability of the blood-histological barrier of the suprarenals caused by the stress (introduction of an irritating mixture) and inflammation.

[Effect of tranquilizers and analgesics on the permeability of the histohematic barriers for sulfacyl in inflammation]. / Vliianie trankvilizatorov i anal'getikov na pronitsaemost' gisto-gematicheskikh bar'erov dlia sul'fatsila v usloviiakh vospaleniia

The effect of neurotropics (analgetics and tranquilizers) on the permeability of histo-blood barriers in normalcy and pathology was wound to be dissimilar. In tests conducted on intact rats the studied neurotropic agents used in pharmacological doses did not affect the permeability of the histological-blood barriers of the brain and spleen with respect to the indicator--sodium sulfacyl. In rats with an inflammation focus the same drugs produced changes of the said factor, not always similar in their orientation (rise of fall).