ABSTRACT
Studies of a relationship between the severity of the developing secondary tissue hypoxia and reduction of the neutrophil phagocytic activity in patients with combined maxillofacial and craniocerebral injuries of varying severity have prompted the authors to include ultraviolet irradiation of the blood and essential therapy in the complex of therapeutic measures aimed at prevention of pyoinflammatory complications with due consideration for the severity of secondary tissue hypoxia detected in the patients on admission to hospital.
Subject(s)
Blood Transfusion, Autologous , Blood/radiation effects , Brain Injuries/therapy , Maxillofacial Injuries/therapy , Multiple Trauma/therapy , Phosphatidylcholines/therapeutic use , Ultraviolet Therapy , Wound Infection/prevention & control , Adolescent , Adult , Blood Transfusion, Autologous/methods , Brain Injuries/complications , Combined Modality Therapy/methods , Evaluation Studies as Topic , Female , Humans , Male , Maxillofacial Injuries/complications , Middle Aged , Multiple Trauma/complications , Oxygen Consumption/drug effects , Phagocytosis/drug effects , Ultraviolet Therapy/methodsABSTRACT
Study of the relationship between the time course of secondary tissue hypoxia development and changes in the neutrophilic phagocytic activity, which was carried out in 65 patients with combined maxillofacial and craniocerebral injury, has revealed a detrimental effect of hypoxia on antibacterial defense factors of the body, this effect being conductive to development of pyoinflammatory complications; this should be borne in mind when planning treatment strategy.