ABSTRACT
Following treatment with stimulant medications for symptoms of attention deficit disorder, Gilles de la Tourette's syndrome occurred in 15 patients. Early signs of Tourette's syndrome may be difficult to distinguish from hyperactive and attention disordered symptoms, leading the clinician to consider treatment with stimulants. In these Tourette's-susceptible patients, stimulants may exacerbate severe motor and phonic tics, requiring discontinuation of administration of stimulants and institution of haloperidol therapy for tic control. Clinical evaluation for tics and Tourette's syndrome in children and their families should precede and dictate use of stimulant medications in children.
Subject(s)
Amphetamines/adverse effects , Tourette Syndrome/chemically induced , Acute Disease , Attention Deficit Disorder with Hyperactivity/drug therapy , Child , Child, Preschool , Dextroamphetamine/adverse effects , Humans , Male , Methylphenidate/adverse effectsABSTRACT
Following treatment with stimulant medications for symptoms of attention deficit disorder, Gilles de la Tourette's syndrome occurred in 15 patients. Early signs of Tourette's syndrome may be difficult to distinguish from hyperactive and attention disordered symptoms, leading the clinician to consider, treatment with stimulants. In these Tourette's-susceptible patients, stimulants may exacerbate severe motor and phonic tics, requiring discontinuation of administration of stimulants and institution of haloperidol therapy for tic control. Clinical evaluation for tics and Tourette's syndrome in children and their families should precede and dictate use of stimulant medications in children.
Subject(s)
Attention Deficit Disorder with Hyperactivity/drug therapy , Central Nervous System Stimulants/adverse effects , Tourette Syndrome/chemically induced , Child , Dextroamphetamine/adverse effects , Haloperidol/adverse effects , Humans , Male , Methylphenidate/adverse effects , Tourette Syndrome/geneticsSubject(s)
Counseling , Epilepsy , Adolescent , Emotions , Female , Humans , Male , Peer Group , Schools , Social AdjustmentABSTRACT
The myelographic findings of enlarged nerve roots in a patient with Charcot-Marie-Tooth disease is found to be identical to those of Hypertrophic Interstitial Neuritis and Neurofibromatosis. The hypertrophy of the roots may represent a single response to different noxious stimuli. Clinical and laboratory differentiation are given for the diseases.
