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2.
Anesthesiology ; 131(2): 238-253, 2019 08.
Article in English | MEDLINE | ID: mdl-31094750

ABSTRACT

BACKGROUND: The number of pregnancy-related deaths and severe maternal complications continues to rise in the United States, and the quality of obstetrical care across U.S. hospitals is uneven. Providing hospitals with performance feedback may help reduce the rates of severe complications in mothers and their newborns. The aim of this study was to develop a risk-adjusted composite measure of severe maternal morbidity and severe newborn morbidity based on administrative and birth certificate data. METHODS: This study was conducted using linked administrative data and birth certificate data from California. Hierarchical logistic regression prediction models for severe maternal morbidity and severe newborn morbidity were developed using 2011 data and validated using 2012 data. The composite metric was calculated using the geometric mean of the risk-standardized rates of severe maternal morbidity and severe newborn morbidity. RESULTS: The study was based on 883,121 obstetric deliveries in 2011 and 2012. The rates of severe maternal morbidity and severe newborn morbidity were 1.53% and 3.67%, respectively. Both the severe maternal morbidity model and the severe newborn models exhibited acceptable levels of discrimination and calibration. Hospital risk-adjusted rates of severe maternal morbidity were poorly correlated with hospital rates of severe newborn morbidity (intraclass correlation coefficient, 0.016). Hospital rankings based on the composite measure exhibited moderate levels of agreement with hospital rankings based either on the maternal measure or the newborn measure (κ statistic 0.49 and 0.60, respectively.) However, 10% of hospitals classified as average using the composite measure had below-average maternal outcomes, and 20% of hospitals classified as average using the composite measure had below-average newborn outcomes. CONCLUSIONS: Maternal and newborn outcomes should be jointly reported because hospital rates of maternal morbidity and newborn morbidity are poorly correlated. This can be done using a childbirth composite measure alongside separate measures of maternal and newborn outcomes.


Subject(s)
Birth Certificates , Delivery, Obstetric/statistics & numerical data , Infant Mortality , Infant, Newborn, Diseases/epidemiology , Maternal Mortality , Puerperal Disorders/epidemiology , Adolescent , Adult , California , Female , Humans , Infant , Infant, Newborn , Middle Aged , Pregnancy , Young Adult
3.
Anesth Analg ; 127(5): e84, 2018 11.
Article in English | MEDLINE | ID: mdl-30138175
5.
Anesth Analg ; 126(5): 1575-1579, 2018 05.
Article in English | MEDLINE | ID: mdl-28858897

ABSTRACT

Bronchial thermoplasty (BT) is a novel, Food and Drug Administration-approved nondrug treatment for patients whose asthma remains uncontrolled despite traditional pharmacotherapy. BT involves application of controlled radiofrequency energy to reduce airway smooth muscle in large- and medium-sized airways. Although BT is often performed under general anesthesia, anesthetic management strategies for BT are poorly described. We describe the anesthetic management of 7 patients who underwent 19 BT treatments in a tertiary academic medical center.


Subject(s)
Airway Management/methods , Anesthesia, Intravenous/methods , Anesthetics, Intravenous/administration & dosage , Asthma/therapy , Bronchial Thermoplasty/methods , Adult , Aged , Airway Management/instrumentation , Airway Management/standards , Anesthesia, Intravenous/standards , Asthma/diagnosis , Bronchial Thermoplasty/instrumentation , Bronchial Thermoplasty/standards , Bronchoscopes/standards , Female , Humans , Male , Middle Aged , Muscle, Smooth/drug effects , Muscle, Smooth/physiology , Retrospective Studies
6.
Anesth Pain Med ; 2(4): 182-5, 2013.
Article in English | MEDLINE | ID: mdl-24223358

ABSTRACT

Carney's complex is a rare autosomal dominantly inherited multiple endocrine neoplasia syndrome that involves spotty skin pigmentations, recurrent cardiac myxomas, endocrine hyperactivity, pituitary adenomas, peripheral nerve tumors, testicular tumors, and ovarian lesions. We present a case of sudden cardiac death in a 40 year old female with a history of Carney's complex with recurrent cardiac myxomas presenting for exploratory laparotomy and enblock adnexal resection of a slowly enlarging right sided ovarian mass. This case highlights the risk for sudden death in these patients as well as the preoperative assessment that should be undertaken by the anesthesiologist as it relates to Carney's complex.

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