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Phytother Res ; 14(1): 43-4, 2000 Feb.
Article in English | MEDLINE | ID: mdl-10641047

ABSTRACT

Dandelions have long been used in herbal medicine for their choleretic, diuretic, antiinflammatory, appetite-stimulating and laxative properties. An antioxidant property can be supposed as a basis of their-therapeutic effects. To understand the mechanism of the drug's action, the effects of natural extracts on a microsomal fraction of rat liver were examined. The extracts diminished the enzymatically induced-lipid peroxidation and reduced the cytochrome c with and without NADPH in a concentration dependent manner.


Subject(s)
Antioxidants/pharmacology , Lipid Peroxidation/drug effects , Microsomes, Liver/drug effects , Plant Extracts/pharmacology , Plants, Medicinal/chemistry , Animals , Microsomes, Liver/metabolism , Rats
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