Subject(s)
Copper/blood , Zinc/blood , Adolescent , Adult , Aging/blood , Child , Female , Humans , Male , Middle Aged , Reference Values , Sex FactorsSubject(s)
Biomarkers, Tumor/blood , Neoplasms/blood , Zinc/blood , Female , Humans , Male , ThailandSubject(s)
Infant Food/analysis , Milk, Human/analysis , Trace Elements/analysis , Animals , Female , Humans , Infant, Newborn , Milk/analysis , ThailandSubject(s)
Erythrocytes/analysis , Porphyrias/epidemiology , Porphyrins/blood , Protoporphyrins/blood , Skin Diseases/epidemiology , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Male , Pedigree , Porphyrias/genetics , Skin Diseases/genetics , ThailandABSTRACT
The plasma zinc and copper and urinary zinc levels were determined by an atomic absorption spectrophotometer technic in 14 patients with hemoglobin (Hb) H disease, 34 patients with beta-thalassemia/Hb E disease and 30 control subjects. Plasma zinc levels were lower and the plasma copper levels were higher in the patients than in controls. The plasma Cu:Zn ratios, a more valuable indicator of body zinc status, increased in the diseased subjects, indicating zinc deficiency. Higher urinary zinc levels in the both Hb H disease and 30 control subjects. Plasma zinc levels were lower and the plasma copper levels were higher in the patients than in controls. The plasma Cu:Zn ratios, a more valuable indicator of body zinc status, increased in the diseased subjects, indicating zinc deficiency. Higher urinary zinc levels in the both Hb H disease and 30 control subjects. Plasma zinc levels were lower and the plasma copper levels were higher in the patients than in controls. The plasma Cu:Zn ratios, a more valuable indicator of body zinc status, increased in the diseased subjects, indicating zinc deficiency. Higher urinary zinc levels in the both Hb H disease and beta-thalassemia/Hb E disease suggest that chronic hemolysis is responsible for hyperzincuria leading to zinc deficiency. The thalassemic patients with undergrowth had higher plasma Cu:Zn ratios than the patients with normal development, indicating a more severe zinc deficiency in the former.
Subject(s)
Copper/blood , Thalassemia/metabolism , Zinc/metabolism , Adolescent , Adult , Child , Female , Growth Disorders/complications , Hemoglobin E , Humans , Male , Middle Aged , Thalassemia/complications , Zinc/blood , Zinc/urineSubject(s)
Paraquat/poisoning , Adolescent , Adult , Antidotes , Autopsy , Female , Humans , Male , Middle Aged , Paraquat/metabolismABSTRACT
A total of 164 breast-milk samples from Thai mothers in different stages of lactation, from one day to over nine months postpartum, and 35 samples of infant milk formulas commercially available were analyzed for their lead concentrations using atomic absorption spectrophotometry. The mean lead concentration in breast milk was 0.0846 +/- 0.0332 microgram per ml which is in the low range and is safe for infants, whereas the mean lead concentration in commercial infant mild formulas was 0.1587 +/- 0.0232 microgram per ml which can become a potential health hazard to infants.
