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Digit J Ophthalmol ; 29(4): 97-1000, 2023.
Article in English | MEDLINE | ID: mdl-38344060

ABSTRACT

Crocodile tear syndrome (CTS) is a late complication of facial nerve palsy characterized by unilateral lacrimation in response to gustatory stimulation. We present 2 cases of patients diagnosed with CTS after recovering from unilateral idiopathic facial nerve palsy. Both patients underwent transconjunctival lacrimal gland incobotulinumtoxinA injection, with doses of 5-16 units. The patients were seen in clinic for post-treatment follow-up at 2 weeks, 3 months, and 6 months. Outcomes were measured by treatment efficacy and adverse drug effects. Following treatment, both patients reported resolution of gustatory lacrimation. The patient treated with 16 U experienced transient ptosis and diplopia following injection, whereas the patient treated with 5-7.5 U experienced no adverse effects.


Subject(s)
Autonomic Nervous System Diseases , Bell Palsy , Blepharoptosis , Botulinum Toxins, Type A , Congenital Cranial Dysinnervation Disorders , Facial Paralysis , Jaw Abnormalities , Lacrimal Apparatus Diseases , Lacrimal Apparatus , Neuromuscular Agents , Reflex, Abnormal , Toxins, Biological , Humans , Lacrimal Apparatus/innervation , Botulinum Toxins, Type A/pharmacology , Botulinum Toxins, Type A/therapeutic use , Neuromuscular Agents/pharmacology , Neuromuscular Agents/therapeutic use , Lacrimal Apparatus Diseases/diagnosis , Lacrimal Apparatus Diseases/drug therapy , Facial Paralysis/complications , Facial Paralysis/drug therapy , Bell Palsy/complications , Bell Palsy/drug therapy , Autonomic Nervous System Diseases/complications , Autonomic Nervous System Diseases/drug therapy , Toxins, Biological/pharmacology , Toxins, Biological/therapeutic use
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