[The role of the "milk" factor in the transmission of Campylobacter infection]. / Izuchenie roli "molochnogo" faktora peredachi kampilobakterioznoi infektsii.

The epidemiological survey of the foci of campylobacteriosis confirmed the activity of the "milk" factor in the transmission of this enteric infection. The proliferation of Campylobacter in milk corresponded to the general regularities of the growth of bacterial population in the closed system. Most of the Campylobacter strains under study retained their viability in cooled boiled milk for a longer time.

[Current parameters of the epidemiological process in campylobacteriosis]. / Nekotorye sovremennye parametry épidemiologicheskogo protsessa kampilobakterioza.

Data on some parameters of the epidemic process of campylobacteriosis in the Ukraine are presented. Campylobacteriosis patients were found to constitute 1.9 +/- 0.095% of all examined patients with acute enteric infections (AEI). No statistically significant difference in the proportion of campylobacteriosis among child and adult AEI patients was established. The proportion of sick persons at the period of the spring-summer rise in morbidity was 71.5%. A definite relationship between the epizootic and epidemic processes in campylobacteriosis was noted. In the Ukraine the predominant infective agent was Campylobacter jejuni belonging mainly to serotype Lio and biotype 1. Quite frequently campylobacteriosis was found to be accompanied by mixed infections.

[The cytopathogenic activity of Campylobacter isolated from different sources]. / Tsitopatogennaia aktivnost' kampilobakterii, vydelennykh iz razlichnykh istochnikov.

The data on the cytopathogenic activity of campylobacteria isolated from different sources are presented. 84.7 % of the isolated campylobacteria have been shown to possess cytopathogenicity with respect to Hep-2 cell cultures. The greatest number of highly cytopathogenic strains (52.6 %) has been registered among clinical isolates of campylobacteria. At the same time 44.1 % of highly cytopathogenic strains have been isolated from chickens, which is indicative of the potential danger of poultry as the source of Campylobacter infection. In the course of the epidemiological surveillance of campylobacteriosis the determination of cytopathogenically active Campylobacter strains is necessary.

[The characteristics of the epidemiology of campylobacteriosis under modern conditions]. / Osobennosti épidemiologii kampilobakterioza v sovremennykh usloviiakh.

The results of the clinico-epidemiological study of campylobacteriosis in a concrete area (Kiev and the Kiev region) are presented. The proportion of campylobacteriosis cases was found to be 6.4% among patients hospitalized in connection with acute enteric infections. Hens were most frequently the source of human infection. Thus, at the local poultry farm the proportion of hens contaminated with bacteria of the genus Campylobacter was 44.8%. The possible routes of the spread of Campylobacter infection and the factors of its transmission were established. The most important element of the epidemiological marking of Campylobacter bacteria is the determination of their species and serotype.

[The antibiotic resistance of strains of Campylobacter of different origins]. / Izuchenie antibiotikorezistentnosti shtammov kampilobakterii razlichnogo proiskhozhdeniia.

Antibioticograms of different campylobacteria strains have been analyzed. It is shown possible to develop a system of epidemiological marking on this basis. With this purpose sensitivity of campylobacteria to gentamycin, canamycin, carbenicyllin, tetracylin and erythromycin has been studied. No statistical difference in the average markers of resistance in the studied groups of strains was observed. This permitted supposing that R-plasmids in "human" strains may be isolated not only from the human intestine microflora, but also from other sources (animals, birds, environmental objects) as well. There are found common R-spectra in different groups of strains (Gm Kb Tc Er; Kb and Kb Tc), which confirms the same infection source. The study of antibioticograms of campylobacteria which circulate among people, animals, birds and environmental objects permits revealing regularities of epidemic process in case of campylobacteriosis.

[The fatty acid composition of the total lipids in bacteria of the genus Campylobacter]. / Zhirnokislotnyi sostav summarnykh lipidov bakterii roda Campylobacter.

Composition of fatty acids of total lipids in home strains of campylobacteria has been studied. Lipids of all the strains of C. jejuni and C. coli mainly consist of saturated fatty acids (from 75.7 to 78.7%) with predominance of tetradecanoic and hexadecanoic fatty acids. The level of unsaturated fatty acids is considerably lower (from 21.0 to 22.5%); These acids are mainly presented by hexadecene acid. Qualitative composition of fatty acids of total lipids in C. jejuni and C. coli does not permit using it for differentiation within these species.

[The epidemiological and clinical characteristics of campylobacteriosis in Ukraine]. / Epidemiologicheskie i klinicheskie osobennosti kampilobakteroza v Ukraine.

Clinical course and epidemiological features of campylobacteriosis in Ukraine are described. The disease accounts for 11.2% of the total number of acute enteric infectious cases. Ratio of bacterial contamination of hens and their role in spread of campylobacteriosis have been established. Possible ways of transfer of the infection are discussed.

[Zoonotic infections in persons working in plants producing meat and bone meal]. / K voprosu o zoonoznykh infektsiiakh u lits, rabotaiushchikh na zavodakh po proizvodstvu miaso-kostnoi muki.

The present study has revealed that persons working at offal and bone processing plants show no specific pathology, peculiar to such plants, in the state of their health and severe mass diseases among these persons are absent. Nevertheless, rather frequent occurrence of erysipeloid should be noted. The survey of workers employed at different stages of the production process has revealed the presence of ornithosis, listeriosis and leptospirosis infections. No clinically manifest cases of these diseases have been detected. The infection of individual workers occurs in the process of production as the result of contacts with infected raw materials of animal origin. For preventing the possible spread of infection great attention should be paid to sanitary, hygienic and epidemiological measures.