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1.
Opt Express ; 23(4): 4357-68, 2015 Feb 23.
Article in English | MEDLINE | ID: mdl-25836472

ABSTRACT

This paper presents a polarization microscope using an infrared (IR) full-Stokes imaging polarimeter. The IR polarimeter utilizes an optimized interference-based micropolarizer design, and provides full-Stokes images with resolution of 1608 × 1208 at 35 frames/second. The device fabrication, instrument calibration, performance evaluation, and measurement results are presented. The measurement error of the imaging polarimeter is less than 3.5%, and the standard deviations are less than 2%.

2.
Appl Opt ; 43(31): 5763-71, 2004 Nov 01.
Article in English | MEDLINE | ID: mdl-15540433

ABSTRACT

The fluorescence confocal microendoscope provides high-resolution, in vivo imaging of cellular pathology during optical biopsy. The confocal microendoscope employs a flexible fiber-optic catheter coupled to a custom-built slit-scan confocal microscope. The catheter consists of a fiber-optic imaging bundle linked to a miniature objective and focus assembly. The 3-mm-diameter catheter may be used on its own or routed though the instrument channel of a commercial endoscope, adding microscopic imaging capability to conventional endoscopy. The design and performance of the miniature objective and focus assembly are discussed. Primary applications of the system include diagnosis of disease in the gastrointestinal tract and female reproductive system.


Subject(s)
Catheterization/instrumentation , Endoscopes , Equipment Failure Analysis , Gastrointestinal Diseases/pathology , Genital Diseases, Female/pathology , Microscopy, Confocal/instrumentation , Equipment Design , Feasibility Studies , Female , Humans , Miniaturization/methods , Reproducibility of Results , Sensitivity and Specificity
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