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Summary recommendations for standardization and reporting of metabolic analyses.

Lindon, John C; Nicholson, Jeremy K; Holmes, Elaine; Keun, Hector C; Craig, Andrew; Pearce, Jake T M; Bruce, Stephen J; Hardy, Nigel; Sansone, Susanna-Assunta; Antti, Henrik; Jonsson, Par; Daykin, Clare; Navarange, Mahendra; Beger, Richard D; Verheij, Elwin R; Amberg, Alexander; Baunsgaard, Dorrit; Cantor, Glenn H; Lehman-McKeeman, Lois; Earll, Mark; Wold, Svante; Johansson, Erik; Haselden, John N; Kramer, Kerstin; Thomas, Craig; Lindberg, Johann; Schuppe-Koistinen, Ina; Wilson, Ian D; Reily, Michael D; Robertson, Donald G; Senn, Hans; Krotzky, Arno; Kochhar, Sunil; Powell, Jonathan; van der Ouderaa, Frans; Plumb, Robert; Schaefer, Hartmut; Spraul, Manfred.

Nat Biotechnol ; 23(7): 833-8, 2005 Jul.

Article in English | MEDLINE | ID: mdl-16003371

Subject(s)

Metabolism , Research/standards , Animals , Genomics/standards , Humans , Metabolism/genetics , Metabolism/physiology , Models, Biological , Multivariate Analysis , Oligonucleotide Array Sequence Analysis/standards , Proteomics/standards , Research Design , Specimen Handling

Metabolite profiling: from diagnostics to systems biology.

Fernie, Alisdair R; Trethewey, Richard N; Krotzky, Arno J; Willmitzer, Lothar.

Nat Rev Mol Cell Biol ; 5(9): 763-9, 2004 09.

Article in English | MEDLINE | ID: mdl-15340383

ABSTRACT

The concept of metabolite profiling has been around for several decades, but only recent technical innovations have allowed metabolite profiling to be carried out on a large scale - with respect to both the number of metabolites measured and the number of experiments carried out. As a result, the power of metabolite profiling as a technology platform for diagnostics, and the research areas of gene-function analysis and systems biology, is now beginning to be fully realized.

Subject(s)

Cell Physiological Phenomena , Metabolism , Molecular Diagnostic Techniques , Magnetic Resonance Spectroscopy/methods , Mass Spectrometry/methods , Proteins/chemistry , Proteins/metabolism , Proteomics/methods

Subject(s)

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