ABSTRACT
The authors discuss the mechanisms of compensatory reactions of the human vegetative nervous system, its central and peripheral parts, in breathing a gaseous hypoxic mixture. Five types of neurovegetative reactions of the organism aimed at maintaining the oxygen balance in blood were distinguished. The interrelationship of values reflecting the activity of the central and peripheral parts of the vegetative nervous system in exposure to emergency effects is discussed.
Subject(s)
Autonomic Nervous System/physiology , Hypoxia/physiopathology , Oxygen/blood , Adolescent , Adult , Aged , Female , Humans , Hypoxia/blood , Male , Middle AgedABSTRACT
The paper is concerned with the data on change in the blood level of ACTH, STH, TSH, cortisol, T3, insulin, C-peptide during a 25-minute session of respiration using a gaseous hypoxic mixture with 10% oxygen (GHM-10). The investigation was performed in 23 healthy volunteers. Change in the hormonal status, characteristic of a moderate stress-reaction, was observed in 60% of the examinees. It was found out that during a GHM-10 session a degree of change in function of the studied factors of the endocrine system showed correlation with change in the activity of the autonomic nervous system.
Subject(s)
Endocrine Glands/physiopathology , Hypoxia/physiopathology , Adult , Endocrine Glands/drug effects , Female , Hormones/blood , Humans , Hypoxia/blood , Male , Radiation-Protective Agents/administration & dosage , Reference Values , Time FactorsABSTRACT
EFfect of linoleic acid hydroperoxide (I) and Fe++ on viscous elastic properties of cell membranes of Ehrlich ascite carcinoma was studied by the method of K+-dependent swelling. It has been shown that the action of 1 and Fe++ is of similar character, and the effect depends on the incubation time and concentration of agents in the incubation mineral solutions. After 2 h incubation the concentration relationships have two patterns characterized by increased swelling at concentrations 10(-6)-10(-5) M and inhibition of this process at concentrations above 10(-5) M. After 4 incubation only the inhibition effect of observed, which seems to reflect the increase of cell membranes rigidity conditioned by the formation of "joints" resulting from the interaction between the products of lipid peroxide oxidation and membrane macromolecules.