ABSTRACT
An eight-year-old child with congenital neurofibromatosis developed rapidly growing synchronous malignant schwannomas in the neck and mediastinum. These tumors, displaying a biphasic pattern of spindle cell sarcoma admixed with mucinous epithelium, represent the eighth and ninth known examples of glandular schwannoma. The clinical and pathological features of this case are detailed and the histogenesis of the tumors discussed.
Subject(s)
Head and Neck Neoplasms/pathology , Mediastinal Neoplasms/pathology , Neoplasms, Multiple Primary/pathology , Neurilemmoma/pathology , Neurofibroma/pathology , Child , Female , Head and Neck Neoplasms/congenital , Head and Neck Neoplasms/etiology , Humans , Mediastinal Neoplasms/etiology , Neoplasm Recurrence, Local/pathology , Neoplasms, Multiple Primary/etiology , Neurilemmoma/etiology , Neurofibroma/congenitalABSTRACT
A minimally symptomatic elderly woman was discovered to have reticulum cell sarcoma involving the uterine cervix on the basis of cervico-vaginal smears taken in the absence of a visible mass lesion. The diagnosis was confirmed by biopsy, and subsequent clinical and operative staging revealed the tumor to be arising in and confined to the uterine cervix. The cytologic features of reticulum cell neoplasia are repetitive and highly characteristic irrespective of its site of origin.
Subject(s)
Lymphoma, Non-Hodgkin/diagnosis , Uterine Cervical Neoplasms/diagnosis , Aged , Cervix Uteri/pathology , Diagnosis, Differential , Female , Humans , Lymphoma, Non-Hodgkin/pathology , Uterine Cervical Neoplasms/pathology , Vaginal SmearsSubject(s)
Skin Neoplasms/pathology , Breast Neoplasms/pathology , Colonic Neoplasms/pathology , Female , Humans , Kidney Neoplasms/pathology , Lung Neoplasms/pathology , Male , Melanoma/pathology , Mouth Neoplasms/pathology , Neoplasm Metastasis , Ovarian Neoplasms/pathology , Rectal Neoplasms/pathology , Stomach Neoplasms/pathologyABSTRACT
Four cases of squamous carcinoma arising in benign cystic teratoma of the ovary are presented, with a detailed correlation of clinical, operative and pathological findings with prognosis. Confinement of tumor to the ovary, with an intact ovarian capsule, is the most important prognostic factor since patients wih extracapsular extension succumb to their disease within 2 years. The literature dealing with this subject is reviewed.
Subject(s)
Carcinoma, Squamous Cell/etiology , Ovarian Cysts/complications , Ovarian Neoplasms/etiology , Teratoma/complications , Aged , Carcinoma, Squamous Cell/pathology , Female , Follow-Up Studies , Humans , Middle Aged , Ovarian Neoplasms/pathology , PrognosisABSTRACT
Two cases of primary leiomyosarcoma of the lung are described, in which primary cytodiagnosis of the tumor type was established prior to surgery. The cytologic features of the cell samples obtained and correlated histopathologic findings are described. The cytologic features of pulmonary leiomyosarcomas are sufficiently characteristic to allow definitive diagnosis, if representative cell samples are obtained.
Subject(s)
Leiomyosarcoma/diagnosis , Lung Neoplasms/diagnosis , Aged , Cell Nucleus/pathology , Chromatin/pathology , Cytodiagnosis , Cytoplasm/pathology , Female , Humans , Leiomyosarcoma/pathology , Lung Neoplasms/pathology , Male , Middle AgedSubject(s)
Cesarean Section/adverse effects , Peritonitis/etiology , Vernix Caseosa , Female , Humans , Infant, Newborn , PregnancyABSTRACT
Rhabdomyosarcoma of the urinary bladder in adults is exceedingly rare. Reported cases have been of the embryonal botryoid type, as seen in children. We will describe a case of pleomorphic rhabdomyosarcoma occurring in the urinary bladder of an adult. In this case, we noted striking intraepidermal migration of tumor cells, resembling the epidermotropic growth characteristic of tumor cells in Paget disease of the breast. The pathological features of this apparently unique case form the subject of this report.
