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Parasite ; 22: 20, 2015.
Article in English | MEDLINE | ID: mdl-26088504

ABSTRACT

A 72-year-old man consulted in November 2012 for abdominal pain in the right upper quadrant. The patient had a history of suspected hepatic amebiasis treated in Senegal in 1985 and has not traveled to endemic areas since 1990. Abdominal CT scan revealed a liver abscess. At first, no parasitological tests were performed and the patient was treated with broad-spectrum antibiotics. Only after failure of this therapy, serology and PCR performed after liver abscess puncture established the diagnosis of hepatic amebiasis. The patient was treated with metronidazole and tiliquinol-tilbroquinol. Amebic liver abscess is the most frequent extra-intestinal manifestation. Hepatic amebiasis 22 years after the last visit to an endemic area is exceptional and raises questions on the mechanisms of latency and recurrence of these intestinal protozoan parasites.


Subject(s)
Liver Abscess, Amebic/diagnosis , Acute Kidney Injury/chemically induced , Aged , Antibodies, Protozoan/blood , Antiprotozoal Agents/therapeutic use , Bacterial Infections/diagnosis , Diagnostic Errors , Drug Therapy, Combination , Entamoeba histolytica/immunology , France/epidemiology , Humans , Liver Abscess, Amebic/diagnostic imaging , Liver Abscess, Amebic/drug therapy , Liver Abscess, Amebic/epidemiology , Male , Metronidazole/therapeutic use , Oxyquinoline/administration & dosage , Oxyquinoline/analogs & derivatives , Oxyquinoline/therapeutic use , Senegal , Time Factors , Tomography, X-Ray Computed , Travel , Trimethoprim, Sulfamethoxazole Drug Combination/adverse effects , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use , West Indies
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