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Klin Lab Diagn ; 62(1): 30-4, 2017 Jan.
Article in Russian | MEDLINE | ID: mdl-30615364

ABSTRACT

The article summarizes data of research studies concerning searching optimal conditions of development of highly specific and highly sensitive immune chromatography test-systems designed for detection of agents of infectious diseases. The analysis was implemented concerning choosing of optimal size of nano-particles of colloid gold and concentration of antibodies for production of conjugate. The alternatives are presented concerning the most frequently used combinations of buffer solutions applied for development and analysis of immune chromatography test-systems. The preferences are established in the field of characteristics of membranes used in composition of multi-membrane composite of immune chromatographic test-systems.


Subject(s)
Chromatography , Communicable Diseases/immunology , Immunoconjugates/immunology , Nanoparticles/chemistry , Antibodies/immunology , Communicable Diseases/diagnosis , Gold Colloid/chemistry , Humans , Immunoconjugates/isolation & purification , Membranes, Artificial
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