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Eksp Klin Farmakol ; 75(4): 17-9, 2012.
Article in Russian | MEDLINE | ID: mdl-22702105

ABSTRACT

Experiments on mice with streptozotocin-induced diabetes mellitus and stress-induced erosive ulcerous damage of the mucous membrane of stomach showed evidence of the preventive activity of deanol aceglumate in the course of peroral introduction at a dose of 250 mg/kg per 24 h during 4 days. This effect is accompanied by activation of the peristalsis of bowels and by an increase in the blood flow in the wall of stomach.


Subject(s)
Anti-Dyskinesia Agents/pharmacology , Deanol/pharmacology , Diabetes Mellitus, Experimental/prevention & control , Stomach Ulcer/prevention & control , Stress, Physiological , Animals , Diabetes Mellitus, Experimental/physiopathology , Mice , Peristalsis/drug effects , Stomach/blood supply , Stomach/physiopathology , Stomach Ulcer/physiopathology
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