[Topographic features of the embryogenesis of human adrenal glands]. / Topografichskie osobennosti nadpochechnykh zhelez cheloveka v émbriogeneze.

The investigation of embryotopography of adrenals was performed on 95 embryo and 5-12 weeks old prefetus preparations, by microscopy, graphic and plastic reconstruction. It was abolished that adrenals develop in close morphologic correlation with temporary (primary kidneys, sex glands) and persistent (secondary kidneys) organs of embryonic retroperitoneal space. Developing in close correlation with derivatives of visceral layer of mesoderm (dorsal mesogastrium, mesocolon), adrenals, especially the left one are covered by an additional peritoneal layer during prefetal period.

[Development of the ductule system of the epididymis in the prenatal period of human ontogeny]. / Razvitie kanal'tsevoi sistemy pridatka iaichka v prenatal'nom periode ontogeneza cheloveka.

In 285 human embryos, prefetuses, fetuses and newborns by means of a complex of morphological methods, development of the epididymal canalicular system has been studied. The anlage of the epididymal canalicular system is stated to appear in embryos 13.0-17.0 mm long (the 6th week of development) and is presented as an accumulation of epithelial cells and primary germ cells between reducing glomeruli and mesonephric canaliculi. The canalization process of the cellular accumulations and their transformation into real canaliculi takes place during the first half of the prefetal period (the 8th week of development). Further growth and development of the epididymal canaliculi takes place in the craniocaudal direction and by the end of the prefetal period (the 12th week) the canaliculi of the head are already formed, they have a twisted course; within the limits of the body and tail they are yet poorly differentiated and their course is nearly straight. During the fetal period of ontogenesis, further differentiation of the epididymal parts occurs and structure of their canaliculi becomes more complex. They acquire a twisted course in all the parts of the organ; by the end of the fetal period the form and structure of the epididymal canaliculi resemble those of the definitive organ.

[Topographic anatomical interrelation of the lumbar triangles with the organs and adipose tissue formations of the retroperitoneal space]. / Topografoanatomicheskie vzaimootnosheniia poiasnichnykh treugol'nikov s organami i kletchatochnymi obrazovaniiami zabriushinnogo prostranstva.

The investigation has been carried out in 96 corpses of fetuses, newborns and mature persons by means of preparation methods, injection of fatty formations of the retroperitoneal space, superior urinary pathways and vessels with x-ray contrast masses and subsequent roentgenography. The area of the lumbar triangles is subjected to certain fluctuations and only in some cases they are absent. The kidneys, peritoneal part of the ureters, duodenum, pancreas, aorta and inferior vena cava in the projection of the lumbar triangles are not situated. The lumbar triangle can be used for performing drainage, when the organs and formations of the retroperitoneal space are operated on.

[Recapitulation in the development of the components of the counterflow system in the vertebrate metanephros]. / Rekapituliatsiia v razvitii komponentov protivotochnoi sistemy metanefrosa pozvonochnykh.

The investigation has been performed on 107 renal preparations obtained from persons of various age (from 5-month-old fetuses up to 45 years of age), certain representatives of other classes of the Vertebrata are also included: fish, amphibia, reptile and mammalia at various stages of pre- and postnatal periods of ontogenesis by means of preparing graphic and plastic reconstructive models, histological investigation and microdissection. The complexity of the intrarenal branching of derivatives of the mesonephric duct diverticulum, development and structure of the canalicular part in nephrons directly depend on the phylogenetic position of the animal. Complexity of the nephron architectonics occurs along the progressive line of taxonomic groups of higher Vertebrata. The nephron loop becomes longer, thin segment of the nephron canalicular part increases in its length and, at last, in mammalia a cone-shaped fasciculus appears as a structural-functional unit of the osmoregulating apparatus of the constant kidney. In the comparative anatomical and comparative embryological aspects recapitulation is observed concerning certain morphological signs of derivatives of the metanephric duct and nephron.

[A method of dislocation of mesoperitoneally disposed portions of the large intestine]. / Sposob dislokatsii mezoperitoneal'no raspolozhennykh uchastkov tolstoi kishki.

In order to decrease the amount of postoperative complications by means of preventing alterations of blood circulation and of the transplant function a method of dislocation of mesoperitoneally disposed portions of the colon has been developed and introduced into practice which consisted in the formation of the mesenterium preventing a bend and trauma of the vascular pedicle. The method was used in 63 patients with idiopathic megadolichocolon. In 80% of the patients there were no complications in the early and postoperative period.

[Growth of the jugular lymph sacs and establishment of the topography of the cervical portion of the thoracic duct during early human ontogenesis]. / Razvitie iaremnykh limfaticheskikh meshkov i stanovlenie topografii sheinogo otdela grudnogo protoka v rannem ontogeneze cheloveka.

In 196 human embryos, prefetuses, fetuses and newborns, by means of a complex of morphological methods, development of the jugular lymphatic sacs and the process of settling of the thoracic duct cervical part topography have been studied. The jugular lymphatic sac anlages take place on the 6th week of the development. From the lymphatic cleft, situating in the mesenchyme near the anterior cardinal veins, multichambered cavities laid with endotheliocytes are forming,--the jugular lymphatic sacs. Connection of the initially close lymphatic sacs with the venous system takes place secondarily by the end of the embryonic period of development. In the area of the sac ostia a valve is formed, that makes morphological premises for unidirected lymph flow into the venous system. The lymph nodes developing at the place of the reducing jugular lymphatic sacs, ensure formation: from the left jugular lymphatic sac--the cervical part of the thoracic duct, from the right jugular lymphatic sac--the right lymphatic duct and the jugular and the subclavicular lymphatic trunks. Variability in the form and topography of these structures are determined both by the form and construction of the jugular lymphatic sacs and by developmental peculiarities of the lymph nodes at their place. The process of settling of the thoracic duct cervical part topography depends on age changes of its size and form, as well as on development of structures situating nearby, and by the time of birth it is not completed.

[Transformation of the kidney pelvis and the major and minor calices during their development]. / Transformatsiia pochechnoi lokhanki, bol'shikh i malykh chashek v protsesse ikh razvitiia.

The investigation has been performed in 28 series of histological sections of human embryos and prefetuses (4-20 weeks of the intrauterine development) and in 17 fetal corpses by means of certain histological methods, preparation of graphic reconstructive models, microscopy and fine preparation. The structural form of the definitive organ renal pelvis is demonstrated to depend on the ramification type of the metanephric duct derivatives. This is stipulated by interinductive processes of the ureteral sprout and metanephrogenic tissue. Quantitative and qualitative characteristics of the diverticulum ramification of the mesonephric duct during embryonic period of the prenatal ontogenesis predetermine the number of the calyces renalis majors and minors in the metanephros.

[Spatial organization of the lesser peritoneal sac during the early stages of human ontogeny]. / Prostranstvennaia organizatsiia malogo peritoneal'nogo meshka na rannikh étapakh ontogeneza cheloveka.

In 63 series of histological sections of human embryos and prefetuses (4-13 weeks) and in 30 corpses of fetuses and stillborns it has been stated that during the 4th week certain changes occur resulting in formation of the lesser peritoneal sac. It further develops into 3 sections: vestibulum bursae omentalis, bursa omentalis proper and cavity of the omentum majus. Spatial-temporal organization of the lesser peritoneal sac is neither connected with development of separate organs or structures, nor with independent growth, but with the process of development of the whole organocomplex of the upper part of the abdominal cavity, formation of topography and organs' fixation, growth peculiarities of the dorsal mesogastrium. The bursa omentalis proper is forming at the expense of retransformation of the hepatogastric pocket, dependent on growth of the dorsal mesogastrium and on a change in the stomach position. The vestibulum bursae omentalis appears in connection with development and formation of the liver topography, lesser omentum and duodenum. The right pulmoesophagial pocket is interrupted by a developing diaphragm with formation of the superior torsion of the bursa omentalis. Disorders in fixation processes of the organs in the superior part of the abdominal cavity and formation of the bursa omentalis topography can serve as a morphological prerequisite for cysts developing in the retroperitoneal space and hernias of the foramen epiploicum.

[Development of the thoracic duct in the prenatal period of human ontogeny]. / Razvitie grudnogo protoka v prenatal'nom periode ontogeneza cheloveka.

In 40 series of histological sections performed in human embryos and prefetuses from 4 up to 20 weeks of development, as well as in 20 corpses of fetuses and stillborns, it has been stated that the anlage of the thoracic duct appear in 6-7-week-old fetuses as lymphatic clefts surrounded with mesenchymal cells that are situated near large veins in the areas of the most active morphogenesis. Connecting with each other, the clefts form the jugular and retroperitoneal lymph sacs and a well branching network of canals. From the latter, on the 7th-8th week of development a plexus of lymph vessels appear, and later on (on the 8th-9th week)--bilaterally situating trunks of the thoracic duct. Further development of the thoracic duct is connected with the lymph nodes formation, their germs appear on the 9th-10th week along the course of the left trunk, as well as along the ductal branches and anastomoses. The formation of the lymph nodes results in reduction of some trunks and plexuses of the thoracic duct. Owing to this, its form in 14-15-week-old prefetuses resembles the one in newborns. Disturbances in the formation processes of the lymph nodes along the course of the reducing ductal areas, as well as their formation along the course of its main trunk can result in various structural variants of the thoracic duct in children and grown-up persons. Histogenesis of the thoracic duct wall and formation of the lymph nodes are not completed by birth.