Hidrotórax agudo como complicaçäo da diálise peritoneal: relato de um caso e revisäo da literatura / Acute hydrothorax as a complication of peritoneal dialysis: report of a case and literature review

Os autores apresentam um caso incomum de paciente com pancreatite aguda e insuficiência renal aguda que necessitou de diálise peritoneal e desenvolveu quadro de desconforto respiratório decorrente de um hidrotórax agudo como complicaçäo de processo dialítico. O diagnóstico foi feito pelo elevado nível de glicose no líquido pleural (455mg/dL) e concomitante glicemia de 81mg/dL. Esta intercorrência parece decorrer de um defeito diafragmático que comunica as cavidades peritoneal e pleural. O tratamento consiste na pronta interrupçäo da diálise peritoneal, com melhora da sintomatologia

[Acute hydrothorax as a complication of peritoneal dialysis: report of a case and review of the literature]. / Hidrotórax agudo como complicação da diálise peritoneal: relato de um caso e revisão da literatura.

Report a case of a patient suffering from acute pancreatitis with renal failure, who needed peritoneal dialysis and developed acute hydrothorax as a complication of the procedure. The diagnosis was made by the high levels of glucose on pleural effusion (455 mg/dL) and glycemia of 81 mg/dL). This complication probably occurs because of a pathological diaphragmatic defect, communicating peritoneal and pleural cavities. The treatment consists of prompt interruption of peritoneal dialysis with improvement of symptomatology.

[Action of 3,5,3'-triiodothyronine (T3) on Walker's 256 carcinosarcoma development]. / Ação da 3,5,3'-triiodotironina (T3) sobre a evolução do carcinossarcoma 256 de Walker.

In order to verify the effects of triiodothyronine (T3) administration in animals bearing Walker tumor, the authors have carried out an experimental study utilizing Wistar rats inoculated with both ascitic and solid Walker tumor, and Balb/c isogenic mice for the study of spreading of macrophages. The animals were treated with T3 20 micrograms/100 g of body weight and the data were analysed by Chi-square and Mann-Whitney tests. The authors conclude that T3 increases significantly the survival of rats bearing Walker tumor, and the spreading of macrophages when inoculated into the peritoneal cavity of mice. The hormone does not alter the weight of tumor mass. These results could be explained by the macrophageal activation and by the synthesis of the tumor necrosis factor.

Study of interactions between Listeria monocytogenes and experimental tumors.

OBJECTIVE: to verify the effects of Listeria monocytogenes (LM) inoculation in the survival of animals bearing Ehrlich's tumor. KIND OF STUDY: experimental. Animals-isogenic mice, Balb/c, female, 19-21 g. Tumor-Ascitic Ehrlich's tumor, dilution of 5 x 10(5) cells/0.1 ml. Bacteria-LM serotype 4a, solution with 7 x 10(3) bacteria (standard sub-lethal dose). Intervention-a) inoculation of LM in mice bearing Ehrlich tumor at the same time as ascitic cells transplantation. b) inoculation of LM seven days before and, again, seven and fourteen days after ascitic cells transplantation. c) to study the effect of using ampicillin 100 mg/kg, im, simultaneously with the inoculation of Ehrlich tumor and LM organisms and, again, 3, 5, 7, 14, 21 and 30 days after the ascitic cells transplantation. ANALYSIS: Chi-square test; p < 0.05 RESULTS AND CONCLUSION: LM increases significantly the survival of mice bearing Ehrlich tumor even when only one inoculum of viable LM was used, seven days before or seven days after the ascitic cells transplantation. The use of ampicillin after the inoculation of LM and tumor transplantation does not alter the survival of mice.

[Effects of H2 blockers on the spreading of macrophages in vitro]. / Efeitos dos bloqueadores H2 sobre o espraiamento de macrófagos "in vitro".

PURPOSE: To verify if cimetidine, ranitidine, and famotidine, when inoculated by ip route in mice, do enhance macrophage activation and whether or not such activation is altered with prior use of sodium thioglycolate. KIND OF STUDY: Experimental. ANIMALS: isogenic, Balb/c mice, 19-21 g. INTERVENTION: The authors used 8 groups of 10 animals. The mice were treated by ip route with cimetidine (100 mg/kg), ranitidine (62.5 mg/kg), and famotidine (50 mg/kg), and were compared to a control group (saline). The method of spreading of macrophages was applied twenty-four hours after the inoculation. The same procedure was repeated on a later stage in groups submitted to a prior treatment with sodium thioglycolate (15 mg/kg). EVALUATION: Kruskal-Wallis and Mann-Whitney's tests were used. RESULTS: Inoculation of anti-H2 drugs in the peritoneal cavity of mice significantly enhances the spreading of macrophages independently of the presence of a peritoneal irritant.