Subject(s)
B-Lymphocytes/immunology , Periodontitis/immunology , T-Lymphocytes/immunology , Adult , Cell Movement , Female , Humans , Leukocyte Count , Male , Middle Aged , Neutrophils/immunology , Rosette FormationABSTRACT
The immune status was examined in 126 patients with malabsorption. Of these, 100 subjects suffered from chronic enteritis of varying severity. Twenty-six patients developed malabsorption after extensive resection of the small intestine. Lymphocyte proliferation and migration of peripheral blood leukocytes exposed to PHA served as immunologic criteria. The secondary immunodeficient status ascertained by the authors correlated with the disease severity and stage. The diets differing in the protein quota (100, 130, 160 g) were applied as the basic therapeutic factor. The best effect was attained with the diet containing 130 g protein which makes it possible to use it for immunocorrection in secondary immunodeficient states of varying etiology.
Subject(s)
Dietary Proteins/administration & dosage , Malabsorption Syndromes/diet therapy , Chronic Disease , Enteritis/diet therapy , Enteritis/immunology , Humans , Immunity, Cellular , Intestine, Small/surgery , Lymphocyte Activation/drug effects , Lymphokines/biosynthesis , Malabsorption Syndromes/immunology , Phytohemagglutinins/pharmacology , Postoperative Complications/diet therapy , T-Lymphocytes/immunologyABSTRACT
Spontaneous migration of peripheral blood leukocytes, lymphocytes and neutrophils was studied in normal subjects. It was found that lymphocytes possess a marked migration activity which is more conspicuous in T cells. Subpopulations of T lymphocytes (T helpers/T mu/ and T suppressors/T gamma) also differed in the migration capacity. T mu proved to be more active as regards migration, while T gamma did not virtually migrate.