ABSTRACT
Ozena belongs to the primary atrophic rhinitis of unknow etiology. The incidence of this disease has markedly decrease in the last decades. We treated 4 patients with ozena between 2000-2005. The diagnosis was confirmed by physical and ENT examination, culture from the nose and CT scan of perinasal sinusis. Ciprofloxacin was aministrated orally in a dose 1,0-0,5 g daily to all patients. Also they were instructed how to clean the nose regularly with an isotonic saline solution and to moisteurse nosa by wotery spray. The treatment with ciprofloxacin was maintained for 4-6 weeks. In 3 causes the result was very good after 2-4 y observation. 1 patient, 16 y. old girl, didn't cooperate therapy propely - she stoped nasal rinsing after some improvement. The second course of treatment seems to get good result (3 months observation). Our and some other authors conclusion is: ciprofloxacin seems to be a promising drug for the treatment of ozena. For good results cleanising the nose regularly is importent as well as antibiotic.
Subject(s)
Anti-Infective Agents/therapeutic use , Ciprofloxacin/therapeutic use , Rhinitis, Atrophic/drug therapy , Administration, Intranasal , Adolescent , Adult , Drug Administration Schedule , Female , Humans , Male , Nasal Decongestants/therapeutic use , Poland , Retrospective Studies , Rhinitis, Atrophic/diagnosis , Treatment OutcomeABSTRACT
OBJECTIVE: To determine the long-term hearing and vestibular outcomes in patients with intractable vertigo caused by unilateral Meniere's disease, who were treated with transtympanic injection of gentamicin. STUDY DESIGN: the study was a long-term analysis of hearing and control of vertigo in patients with unilateral Meniere's disease who received transtympanic gentamicin. METHODS: Pure-tone thresholds and ENG, along with the control of vertigo. Criteria described in 1995 by the American Academy of Otolaryngology - Head and Neck Surgery were used. Patients treated with transtympanic gentamicin had definite Meniere's disease and had intractable vertigo despite optimal medical therapy, no symptoms suggestive of Meniere's disease in the contralateral ear, and serviceable hearing in the contralateral ear. The study analyzed the outcomes of 9 patients for whom follow-up data were available for periods greater than 24 months after transtympanic gentamicin. RESULTS: Complete control of vertigo was obtained in all 9 patients. Profound sensorineural hearing loss occurred only in 1 patient. Hearing was improved in 6 patients, and in 2 was unchanged. CONCLUSIONS: Transtympanic gentamicin therapy is a good method of controlling vertigo and the risk of hearing loss is low.
Subject(s)
Gentamicins/administration & dosage , Hearing/drug effects , Meniere Disease/drug therapy , Tympanic Membrane , Vertigo/drug therapy , Adult , Anti-Bacterial Agents/administration & dosage , Female , Follow-Up Studies , Gentamicins/adverse effects , Humans , Injections , Male , Middle Aged , Time Factors , Treatment OutcomeABSTRACT
The paper presents the results of transtympanic steroid therapy for sadden sensorineural hearing loss in 20 patients. All patients previously underwent a full conventional treatment, without the beneficial effect. Patients were classified into two groups: the first one consisted of 16 patients who received intratympanic Dexaven application just after termination of conventional treatment. The second group received intratympanic treatment 1 or more months after the conventional therapy had been finished. The pattern of intratympanic Dexaven application is presented. The results of treatment are promising (hearing improvement in 7 cases) and the method is both minimally invasive and inexpensive.
Subject(s)
Anti-Inflammatory Agents/therapeutic use , Hearing Loss, Sensorineural/drug therapy , Prednisone/therapeutic use , Administration, Topical , Adolescent , Adult , Anti-Inflammatory Agents/administration & dosage , Female , Hearing Loss, Sensorineural/diagnosis , Humans , Male , Middle Aged , Prednisone/administration & dosage , Severity of Illness Index , Tympanic MembraneABSTRACT
The authors described a technique and presented the results of the modified labyrinthectomy in 9 cases. A labyrinthectomy was performed during the removal of neuromas by translabirynthine approach, in advanced unilateral Meniere disease, in a huge perylimphatic fistula and in a case of labyrinthitis latens. In 3 cases of the neuromas removal the residual hearing was preserved. In remained cases of labyrinthectomy hearing was preserved partially.
Subject(s)
Cholesteatoma, Middle Ear/surgery , Cochlear Duct/surgery , Ear, Inner/surgery , Meniere Disease/surgery , Neuroma, Acoustic/surgery , Otologic Surgical Procedures/methods , Vestibule, Labyrinth/surgery , Adult , Aged , Cholesteatoma, Middle Ear/complications , Cholesteatoma, Middle Ear/physiopathology , Female , Hearing , Humans , Male , Meniere Disease/etiology , Meniere Disease/physiopathology , Middle Aged , Neuroma, Acoustic/complications , Neuroma, Acoustic/physiopathology , Plastic Surgery Procedures/methods , Time Factors , Treatment OutcomeABSTRACT
Involvement of the immunological mechanisms in the pathogenesis of Meniere's disease has been discussed over the past two decades. Nevertheless, we lack well-defined laboratory tests that might confirm the autoimmune background of the disorder. Therefore the diagnosis is often based solely on the patient's clinical profile and the positive response to the immunosuppressive therapy. In this article we present a case of 44 year-old woman with Meniere's disease successfully treated with systemic glucocorticoids. The pathogenesis, diagnosis and management of immune-mediated cases of Meniere's disease are reviewed.
