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BMJ Case Rep ; 20132013 Jan 29.
Article in English | MEDLINE | ID: mdl-23365164

ABSTRACT

A 5-year-old boy presented with neutropenia 9 weeks following the administration of rituximab for management of his steroid-dependent nephrotic syndrome. Extensive investigations failed to identify any underlying cause. In keeping with adult reports, rituximab was thought to be the likely cause for this 'late-onset' neutropenia (LOP). He was treated successfully with granulocyte-colony-stimulating factor. Patients treated with rituximab need to be carefully monitored for LOP.


Subject(s)
Antibodies, Monoclonal, Murine-Derived/adverse effects , Immunologic Factors/adverse effects , Nephrotic Syndrome/drug therapy , Neutropenia/chemically induced , Child, Preschool , Granulocyte Colony-Stimulating Factor/therapeutic use , Humans , Male , Neutropenia/drug therapy , Rituximab
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