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3.
J Clin Pharm Ther ; 36(6): 734-6, 2011 Dec.
Article in English | MEDLINE | ID: mdl-21083675

ABSTRACT

WHAT IS KNOWN AND OBJECTIVE: Propofol, a commonly used sedative, has on rare occasions, been reported to discolour urine green. However, in previous reports, it is uncertain that whether this colour change is dose dependent. We report on a patient who produced dark green discoloration of urine from prolonged propofol infusion, administered for intractable epilepsy. CASE SUMMARY: The colour intensity of the patient's urine was dependent on propofol infusion rate. Reducing propofol infusion rate lightened the colour of the urine, eventually back to normal. WHAT IS NEW AND CONCLUSION: Green discoloration of the urine from propofol infusion is dose dependent. It is usually benign and reversible, as was the case for our patient.


Subject(s)
Anesthetics, Intravenous/adverse effects , Propofol/adverse effects , Urine/chemistry , Adult , Anesthetics, Intravenous/administration & dosage , Color , Dose-Response Relationship, Drug , Humans , Infusions, Intravenous , Male , Propofol/administration & dosage , Status Epilepticus/drug therapy
4.
J Clin Neurosci ; 16(11): 1482-5, 2009 Nov.
Article in English | MEDLINE | ID: mdl-19581090

ABSTRACT

A 57-year-old right-handed man presented with speech disturbance 1 day prior to his admission. The standardized aphasia test batteries showed transcortical sensory aphasia. MRI revealed a left frontal and insular infarct. Positron emission tomography scans also revealed a glucose hypometabolism in the same region as the infarcted area on MRI. Repeated aphasia testing showed that his aphasia only partially improved.


Subject(s)
Aphasia, Wernicke/etiology , Cerebral Infarction/complications , Cerebral Infarction/pathology , Frontal Lobe/pathology , Language , Brain Mapping , Diffusion Magnetic Resonance Imaging/methods , Humans , Male , Middle Aged
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