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1.
Eye (Lond) ; 30(4): 570-6, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26795416

ABSTRACT

PURPOSE: To report the 7-year incidence of uncorrected refractive error in a metropolitan Chinese elderly population. METHODS: The Shihpai Eye Study 2006 included 460/824 (55.8%) subjects (age range 72-94 years old) of 1361 participants in the 1999 baseline survey for a follow-up eye examination. Visual acuity was assessed using a Snellen chart, uncorrected refractive error was defined as presenting visual acuity (naked eye if without spectacles and with distance spectacles if worn) in the better eye of <6/12 that improved to no impairment (≥6/12) after refractive correction. RESULTS: The 7-year incidence of uncorrected refractive error was 10.5% (95% confidence interval (CI): 7.6-13.4%). 92.7% of participants with uncorrection and 77.8% with undercorrection were able to improve at least two lines of visual acuity by refractive correction. In multivariate analysis controlling for covariates, uncorrected refractive error was significantly related to myopia (relative risk (RR): 3.15; 95% CI: 1.31-7.58) and living alone (RR: 2.94; 95% CI 1.14-7.53), whereas distance spectacles worn during examination was protective (RR: 0.35; 95% CI: 0.14-0.88). CONCLUSION: Our study indicated that the incidence of uncorrected refractive error was high (10.5%) in this elderly Chinese population. Living alone and myopia are predisposing factors, whereas wearing distance spectacles at examination is protective.


Subject(s)
Asian People/ethnology , Refractive Errors/ethnology , Aged , Aged, 80 and over , Eyeglasses , Female , Humans , Incidence , Male , Refractive Errors/therapy , Risk Factors , Taiwan/epidemiology , Time Factors , Vision Tests/instrumentation , Visual Acuity/physiology
2.
Eur J Ophthalmol ; 18(1): 66-70, 2008.
Article in English | MEDLINE | ID: mdl-18203087

ABSTRACT

PURPOSE: To investigate the rate of bleb-related endophthalmitis over 5 years in a Chinese population. METHODS.:Retrospective chart review. RESULTS: Of 988 trabeculectomies performed over 5 years, one case (0.1%) developed early endophthalmitis caused by Morganella morganii, which was rarely reported in the literature. Six cases (0.6%) developed late-onset endophthalmitis. Mitomycin C significantly increased the risk of late-onset endophthalmitis (p=0.0002). CONCLUSIONS: Physicians should weigh the benefits against the risks of mitomycin C application in performing trabeculectomies.


Subject(s)
Endophthalmitis/microbiology , Eye Infections, Bacterial/microbiology , Postoperative Complications , Trabeculectomy , Adult , Aged , Alkylating Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Asian People/ethnology , China/epidemiology , Drug Therapy, Combination , Endophthalmitis/drug therapy , Endophthalmitis/ethnology , Enterobacteriaceae Infections/drug therapy , Enterobacteriaceae Infections/ethnology , Enterobacteriaceae Infections/microbiology , Eye Infections, Bacterial/drug therapy , Eye Infections, Bacterial/ethnology , Female , Glaucoma/surgery , Humans , Male , Middle Aged , Mitomycin/administration & dosage , Morganella morganii/isolation & purification , Retrospective Studies , Staphylococcal Infections/drug therapy , Staphylococcal Infections/ethnology , Staphylococcal Infections/microbiology , Staphylococcus aureus/isolation & purification , Streptococcal Infections/drug therapy , Streptococcal Infections/ethnology , Streptococcal Infections/microbiology , Viridans Streptococci/isolation & purification , Vitreous Body/microbiology
3.
Eye (Lond) ; 19(5): 540-5, 2005 May.
Article in English | MEDLINE | ID: mdl-15319791

ABSTRACT

PURPOSE: To investigate the impact of stereopsis on vision-related quality of life and general health status of the elderly. METHODS: A quota of 200 subjects aged 65 years or older and had their households registered in Guando district was recruited for a general physical examination including ophthalmic evaluation. A structured questionnaire consisting of seven vision-specific items as well as 36-item short-form survey of the Medical Outcomes Study (SF-36) was administered. Stereoscopic level was divided into three groups: no stereopsis, gross stereopsis, and fine stereopsis. Fisher's exact test was used to detect any difference in subjective visual functioning and Mann-Whitney U test was used for analyses of SF-36 scores. RESULTS: A total of 187 volunteers were recruited and 150 were analysed for stereoscopic levels. There was no significant difference in vision-specific difficulty among the three stereoscopic groups. For SF-36, having no stereopsis scored significantly less than having gross (P=0.005) and fine (P<0.0001) stereopsis in the vitality/energy dimension. General health perception dimension fared significantly lower in the group with no stereopsis compared to the fine stereoscopic group (P=0.01). In multivariate analysis, having fine stereopsis scored significantly higher in the energy/vitality dimension than having no stereopsis (P=0.02). On the other hand, visual impairment imposed significant adverse effect on five vision-specific items and had no significant relationship with the eight dimensions of SF-36. CONCLUSIONS: Defective stereopsis in the elderly imposes no significant adverse effect on vision-related quality of life. However, subjects may feel more exhausted in accomplishing their usual tasks.


Subject(s)
Depth Perception , Quality of Life , Visually Impaired Persons/rehabilitation , Activities of Daily Living , Aged , Aged, 80 and over , Female , Geriatric Assessment/methods , Health Status , Health Status Indicators , Humans , Male , Statistics, Nonparametric , Surveys and Questionnaires , Visual Acuity
4.
Eye (Lond) ; 19(7): 784-7, 2005 Jul.
Article in English | MEDLINE | ID: mdl-15359238

ABSTRACT

PURPOSE: The purpose of the present study was to investigate the incidence and severity of iridial pigmentation under latanoprost topical use on brown eyes in Taiwan. METHODS: Retrospective review study was conducted from April 1999 to October 2001 in the Department of Ophthalmology, Taipei Veterans General Hospital, Taiwan, for glaucoma clinic monthly follow-up patients; 140 open-angle glaucoma patients on 0.005% latanoprost were enrolled. Analyses of iridial pigmentation incidence, grading, patient age distribution, side effect, and time course were performed. Boys-Smith pigment gradation lens was used as standard for semiquantitative iris pigmentation grading. RESULT: Before 0.005% latanoprost use, 90% of the patients enrolled were noted with iridial pigmentation grade I, and 10% were with grade I-II, but not reaching grade II scale standard. A total of 60 patients on 0.005% latanoprost developed increased pigmentation of the iris during the follow-up period. An increase of iris pigmentation was noted after an average of 7.27 months use of latanoprost (range 1-19 months, SD 2.65 months). For iridial pigmentation grading, 57.1, 30.7, 10.0, and 2.1% of our patients were noted to have grade I, II, III, and IV respectively. Most patients with latanoprost-induced iris hyperpigmentation were with grade II iridial pigmentation. There were 15 patients (10.7%) (10 female and five male) with hypertrichosis in the study group who were not compatible with the iridial pigmentation status. Among these patients, female patients had higher incidence of hypertrichosis than males, but this did not bother them. Only four patients (2.8%) were with conjunctiva chemosis and three patients (2.1%) with lid margin hyperpigmentation. CONCLUSION: Contrary to the belief that latanoprost rarely caused iris hyperpigmentation in yellow-brown eyes, our study showed that 42.8% iris hyperpigmentation did occur, especially after continual use for around 7 months. Higher hyperpigmentation incidence were noted in male than in female patients. This might be due to stronger adrenergic incidence in male than in female patients. Although hypertrichosis and increasing eyelid pigmentation together with iridial pigmentation represented a potentially permanent cosmetic side effect, they are very rare and occurred in no more than 3% in our patients. It is a good way to take Boys-Smith pigment gradation lens for iridial pigmentation grading and for long-term continual evaluation. The doctors should exert great care in differentiating drug-induced iris pigmentation and iris nevi from early stage uveal melanoma.


Subject(s)
Antihypertensive Agents/adverse effects , Hyperpigmentation/chemically induced , Iris Diseases/chemically induced , Prostaglandins F, Synthetic/adverse effects , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Child , Female , Glaucoma, Open-Angle/drug therapy , Humans , Hypertrichosis/chemically induced , Latanoprost , Male , Middle Aged , Retrospective Studies , Severity of Illness Index
5.
Am J Ophthalmol ; 132(2): 257-8, 2001 Aug.
Article in English | MEDLINE | ID: mdl-11476690

ABSTRACT

PURPOSE: To report a case of Serratia Marcescens corneal ulcer as a complication of orthokeratology treatment. METHODS: Case report. RESULTS: A 9-year-old male who underwent orthokeratology treatment for 6 months suffered from a corneal ulcer. The refractive state of lesion eye was -5.5D/-1.25D x 180 degrees, and visual acuity was hand motion at 30 cm. He wore a retainer lens, rigid gas permeable lens, overnight for 2 months before the corneal ulcer occurred. Ulcer became worse after tobramycin and gentamycin treatment for 2 days. After ciprofloxacin treatment, the ulcer healed and visual acuity recovered to 20/20 with spectacle correction. Cultures of the cornea tissue and contact lens storage solution both grew Serratia Marcescens, which was sensitive to ciprofloxacin. CONCLUSION: Overnight wearing of a rigid contact lens is a risk factor for a corneal ulcer.


Subject(s)
Contact Lenses/adverse effects , Corneal Ulcer/etiology , Eye Infections, Bacterial/etiology , Serratia Infections/etiology , Serratia marcescens/isolation & purification , Anti-Infective Agents/therapeutic use , Astigmatism/therapy , Child , Ciprofloxacin/therapeutic use , Contact Lenses/microbiology , Cornea/microbiology , Corneal Ulcer/drug therapy , Eye Infections, Bacterial/drug therapy , Humans , Male , Myopia/therapy , Risk Factors , Serratia Infections/drug therapy , Visual Acuity
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