ABSTRACT
Approximately 2,400 laboratories participated in the 1982 Comprehensive Blood Bank Survey of the College of American Pathologists. Fourteen Referee Laboratories were utilized to validate the results of participants and to assure lack of deterioration of the specimens during shipment. Results of the participants in ABO grouping, Rh D typing, special antigen typing, and antibody detection and identification are reported and discussed. Special ungraded studies, which provided additional challenges, and supplementary questions with the responses of participants are also included.
Subject(s)
Blood Banks/standards , ABO Blood-Group System , Blood Grouping and Crossmatching , Hospital Bed Capacity , Humans , MNSs Blood-Group System , Rh-Hr Blood-Group SystemABSTRACT
Results of the 1981 Comprehensive Blood Bank Survey of the College of American Pathologists are reported and summarized in tabular form. Excellent results were achieved by the participants in ABO grouping, Rh typing, and crossmatching. Difficulties were encountered by some of the participants in detecting a very weak anti-D and a naturally occurring anti-E. Ungraded specimens were included in this survey and report as well as responses to additional questions utilized to determine current blood bank practices.
Subject(s)
Blood Banks/standards , Pathology, Clinical/standards , ABO Blood-Group System , Blood Group Incompatibility/diagnosis , Blood Grouping and Crossmatching , Coombs Test , Female , Humans , Infant, Newborn , Male , Pregnancy , Quality Control , Rh-Hr Blood-Group System/immunology , Societies, Medical , United StatesABSTRACT
Chromosome studies on gallbladder adenocarcinoma in a Papago Indian woman were performed. These studies revealed a high degree of aneuploidy including multiple instances of missing chromosomes, extra chromosomes, and chromosome rearrangements. Double minute chromosomes and homogeneous staining regions on chromosomes were present in the cancer cells. To our knowledge this is the first report on the cytogenetic analysis of a gallbladder cancer. Chromosome studies on gallbladder cancers will be of unusual interest because of the relatively high frequency of this rare genetic form of cancer in American Indians.
Subject(s)
Adenocarcinoma/genetics , Chromosome Aberrations , Gallbladder Neoplasms/genetics , Aged , Aneuploidy , Female , Humans , Indians, North AmericanABSTRACT
Results of the 1980 Comprehensive Blood Bank Survey of the College of American Pathologists are summarized in tabular form. The overall mean of correct responses among participating laboratories showed a high degree of correlation with Referee Laboratory results in ABO and Rh D typing as well as in crossmatching. Some problems existed in the identification and recognition of multiple alloantibodies and in the identification of an alloanti-c in the presence of rouleaux. Ungraded sample results are reported as well as responses to questions regarding the current standards of practice in hospital blood banks.
Subject(s)
Blood Banks , Pathology, Clinical/standards , ABO Blood-Group System , Blood Grouping and Crossmatching , Blood Transfusion , Humans , Rh-Hr Blood-Group SystemABSTRACT
The results of the 1979 Comprehensive Blood Bank Survey of the College of American Pathologists are summarized in tabular form and analyzed. Approximately 2400 laboratories participated in this program. Results of ABO grouping, Rh D typing, and compatibility testing were excellent--over 95% of the participating laboratories obtained the correct responses. Some problems were evident in the recognition of an anti-B in a group B individual, and in the identification of an anti-Cw and an anti-Jka. Sixteen percent of participants reported false positive results in typing with anti-N a cell whose phenotype was M. Other ungraded samples were supplied to provide additional unusual challenges and to review the results of the participants. Many of the questionnaires used in 1978 and 1979 contained additional questions which help define blood bank practices during these years. The responses to these questions are also listed.
