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Bull Exp Biol Med ; 162(5): 687-689, 2017 Mar.
Article in English | MEDLINE | ID: mdl-28361434

ABSTRACT

Morphological analysis of the subcutaneous fat was performed in rats after subcutaneous implantation of basic dental plastic materials with different hydrophobic and hydrophilic properties. It was shown that subcutaneous implantation of dental plastics with mostly hydrophobic surface and low biocompatibility induced destructive and inflammatory processes of various intensities, sometimes with allergic component; morphological signs of processes persisted for 6 weeks. Modification of basic plastics using glow-discharge plasma and enhancement of their hydrophilicity and biocompatibility significantly reduced the intensity of destructive and inflammatory processes and ensured more rapid (in 2 weeks) repair of the destroyed tissues with the formation of fibrous capsule around the implant.


Subject(s)
Biocompatible Materials/toxicity , Polymethyl Methacrylate/toxicity , Subcutaneous Fat/drug effects , Animals , Hydrophobic and Hydrophilic Interactions , Implants, Experimental , Male , Materials Testing , Rats, Wistar , Surface Properties
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