ABSTRACT
The authors describe cases of leishmaniasis for which claforan (cefotaxime) has been used, showing an obvious improvement in visceral leishmaniasis in children and a full recovery in cutaneous leishmaniasis in adults.
Subject(s)
Antiprotozoal Agents/therapeutic use , Cefotaxime/therapeutic use , Leishmaniasis/drug therapy , Adult , Child , Child, Preschool , Female , Humans , MaleABSTRACT
The structure of recurrent malignant neoplasms was analysed in a group of patients followed up on a permanent basis after the treatment for skin cancer. Observation of 2801 patients with primary basal and squamous cell skin cancer during 32 years (1975-2006) revealed 740 recurrent malignant neoplasms largely affecting skin, gastrointestinal tract, lungs, mammary and prostate glands.
Subject(s)
Breast Neoplasms/epidemiology , Gastrointestinal Neoplasms/epidemiology , Neoplasms, Multiple Primary/epidemiology , Prostatic Neoplasms/epidemiology , Skin Neoplasms/epidemiology , Aged , Breast Neoplasms/pathology , Carcinoma, Basal Cell/epidemiology , Carcinoma, Basal Cell/pathology , Carcinoma, Squamous Cell/epidemiology , Carcinoma, Squamous Cell/pathology , Diagnosis, Differential , Female , Gastrointestinal Neoplasms/pathology , Humans , Incidence , Male , Mass Screening/methods , Neoplasms, Multiple Primary/pathology , Prostatic Neoplasms/pathology , Retrospective Studies , Russia/epidemiology , Skin Neoplasms/pathologyABSTRACT
The paper describes a case of a long-lasting chronic migrant erythema (ME) in an 82-year-old female, which developed after the bite of an insect (a tick?). The specific feature of this case is an unusual duration (2 years) of a single focus of ME and autopsy of the skin revealed giant cells with centrally arranged 3-5 nuclei and cytoplam with PAS-positive inclusions as tiny (5 m) oblong formations, that may be Borelia.
Subject(s)
Erythema Chronicum Migrans/pathology , Lyme Disease/pathology , Aged , Aged, 80 and over , Borrelia , Female , Humans , Skin/microbiology , Skin/pathologyABSTRACT
Stewart-Treves Syndrome ('STS) is a rare, extremely malignant and quickly progressing tumor. It is angiosarcoma developing in lymphostasis of an arm after radical mastectomy for cancer. The patient aged 80 years was followed-up, in whom STS had developed 19 years after radical mastectomy. Clinical diagnosis was confirmed by pathomorphological examination of dermal biopsy. Advanced age and severe associated diseases made it impossible to carry out specific therapy. The patient died of intoxication and increasing cardio-vascular insufficiency 9 months after the onset of the disease.
