ABSTRACT
The sign of Leser-Trélat in a patient with squamous cell carcinoma of the cervix is reported. This seems to be the first report of this association. Literature was reviewed, try to correlate this entity with acanthosis nigricans and to link this sign with internal malignancy or other kind of epidermal stimuli.
Subject(s)
Carcinoma, Squamous Cell/complications , Dermatitis, Seborrheic/complications , Keratosis/complications , Uterine Cervical Neoplasms/complications , Female , Humans , Middle AgedABSTRACT
The term "metastatic" Crohn's disease is used to define the cutaneous lesions, distant from the gastrointestinal tract and separated from other ulcerations by normal skin, showing granulomatous histology. A case of Crohn's disease with metastatic ulcerations of the vulva, perineum, submammary folds, groins and abdominal fold is presented. In the literature only 26 similar cases were found. Cutaneous manifestations associated to Crohn's disease, its classification and treatment are commented. The excellent response of our case to metronidazole is stressed.
Subject(s)
Crohn Disease/pathology , Skin Diseases/pathology , Aged , Crohn Disease/drug therapy , Female , Humans , Metronidazole/therapeutic use , Skin Diseases/drug therapy , Vaginal Diseases/pathology , Vulvar Diseases/pathologyABSTRACT
E feito um levantamento de 26.025 pacientes internados em hospital geral, no periodo de 1/12/81 a 1/08/83. Neste periodo foram solicitadas 690 consultorias ao Servico de Dermatologia e diagnosticados 85 casos de farmacodermias. As reacoes cutaneas a drogas foram mais comuns em mulheres e na faixa etaria acima dos 40 anos.As drogas mais comumente implicadas foram a ampicilina e a pirazolona, sendo feita correlacao com os quadros clinicos mais comuns que surgiram
