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1.
Ukr Biokhim Zh (1978) ; 62(1): 92-4, 1990.
Article in Russian | MEDLINE | ID: mdl-2336730

ABSTRACT

It is shown that the content of neurospecific dipeptide of homocarnosine in the brain and blood of rats increases considerably after intraperitoneal administration of ethanol. The exogenous leu-enkephalin exerts an effects on the development of the alcoholic organism response.


Subject(s)
Alcoholic Intoxication/metabolism , Brain/metabolism , Carnosine/metabolism , Dipeptides/metabolism , Animals , Carnosine/analogs & derivatives , Carnosine/blood , Enkephalin, Leucine/pharmacology , Rats , Rats, Inbred Strains
2.
Radiobiologiia ; 27(1): 112-5, 1987.
Article in Russian | MEDLINE | ID: mdl-2881321

ABSTRACT

The neuroparalytic syndrome induced by ammonia was compared with the X-radiation-induced cerebral syndrome. It is suggested that the accumulation of ammonia in the brain and liver of rats is one of the reasons for the similarity of the studied syndromes. The fact that ammonia is bound by glutamic acid indicates that the latter is involved in the mechanisms of ammonia utilization and in the radioprotective properties manifestation.


Subject(s)
Ammonia/metabolism , Brain Diseases/etiology , Brain/metabolism , Liver/metabolism , Radiation Injuries, Experimental/metabolism , Ammonia/blood , Animals , Brain Diseases/drug therapy , Brain Diseases/metabolism , Dose-Response Relationship, Drug , Dose-Response Relationship, Radiation , Glutamates/metabolism , Glutamates/therapeutic use , Glutamic Acid , Paralysis/chemically induced , Paralysis/drug therapy , Paralysis/metabolism , Rats , Rats, Inbred Strains , Syndrome
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