ABSTRACT
Original method of baroreflex activation and deactivation was described. Bradycardia and vasodilatation of the forearm vessels were observed at baroreflex activation. Tachycardia and forearm blood flow reduction were observed at baroreflex deactivation. The sensitivity of baroreflex heart component vas shown to depend upon the arterial pressure and a baseline cardiac cycle duration in both normo- and hypertensive subjects.
Subject(s)
Baroreflex/physiology , Forearm/blood supply , Heart Rate/physiology , Hypertension/physiopathology , Adult , Aged , Blood Pressure/physiology , Female , Humans , Hypertension, Renal/physiopathology , Lower Body Negative Pressure , Male , Middle Aged , Neurocirculatory Asthenia/physiopathology , Regional Blood FlowABSTRACT
Blood flow in human forearm and arterial pressure gradient in conduit arteries of forearm were studied during reactive hyperemia caused by arterial occlusion for 1, 3, 5, 15 and 30 min. The mechanisms of tonus formation and regulation of these vessels are heterogeneous. The precapillary vessels dilate during arterial occlusion whereas conduit arteries dilate only after restoration of free blood flow during early phase of reactive hyperemia as a result of increased flow velocity. The normalisation of resistance of precapillary and conduit arteries during reactive hyperemia also develops independently.
Subject(s)
Capillary Resistance/physiology , Forearm/blood supply , Hyperemia/physiopathology , Vascular Resistance/physiology , Adult , Arteries/physiology , Capillaries/physiology , Hemodynamics/physiology , Humans , Reference Values , Time Factors , TourniquetsABSTRACT
To evaluate the contribution of cortical and peripheral reflexes in originating pressor reaction, the carotid baroreceptor and sympatho-adrenal activity (according to plasma noradrenaline, adrenaline and dopamine levels) were studied during voluntary handgrip. Differences were found in the pattern of adrenergic responses during and after contraction when only muscle blood receptors were activated by the products of anaerobic metabolism. The data indicate that the inhibition of a heart component of carotid baroreceptor is related to central motor command.
Subject(s)
Blood Pressure , Carotid Sinus/physiology , Catecholamines/blood , Reflex/physiology , Sports , Weight Lifting , Adrenal Glands/physiology , Adult , Female , Heart Rate , Humans , Male , Muscle Contraction , Sympathetic Nervous System/physiologyABSTRACT
The experience in the treatment of 107 patients with iatrogenic traumatism of vessels shows that damage to the main veins may be regarded as the most serious lesion. Operations on the vessels carried out in the first hours after the damage permit one to limit the volume of surgery and to prevent a number of complications. Exception is made for children under 3 when post-catheterization arterial thromboses caused by traumas of a considerable part of the intima require removal.