ABSTRACT
Sodium hypochlorite, administrated intravenously and intraperitoneally, leads to normal oxygen balance, metabolism and motility of small intestine in peritonitis. Anti-hypoxia effect of this substance is realized by an increase of oxygen content in the blood. It is useful to use sodium hypochlorite in general peritonitis for antibacterial therapy and against tissue hypoxia without side effects.
Subject(s)
Intestine, Small/drug effects , Oxygen Consumption/drug effects , Peritonitis/drug therapy , Sodium Hypochlorite/pharmacology , Animals , Gastrointestinal Motility/drug effects , Intestine, Small/metabolism , Intestine, Small/physiology , Oxygen/blood , Rats , Sodium Hypochlorite/administration & dosage , Sodium Hypochlorite/therapeutic useABSTRACT
Under observation there were 174 patients with purulent wounds, 54 of them were treated with application of 0.06% solution of sodium hypochlorite, and 20 patients made up a control group and were treated by traditional methods. It was found that the application of the solution of sodium hypochlorite results in sharp elevation of susceptibility of wound microflora to antibiotics and facilitates more rapid debridement of the wounds and makes the treatment at the hospital 3.7 and 2.4 times shorter correspondingly (as compared with the control group).
Subject(s)
Anti-Bacterial Agents/administration & dosage , Bacterial Infections/drug therapy , Mastitis/drug therapy , Proctitis/drug therapy , Skin Diseases, Infectious/drug therapy , Sodium Hypochlorite/administration & dosage , Administration, Cutaneous , Adolescent , Adult , Aged , Drug Therapy, Combination , Humans , Middle AgedABSTRACT
Hemosorption was performed in 8 patients with a resistant status epilepticus and serial epileptic attacks; arrest of the attacks correlated with significantly faster and stabler normalization of the circulating levels of immune complexes and of the phagocytic activity of neutrophils as compared to the same parameters in patients receiving a course of conventional anticonvulsive and dehydration therapy without hemosorption. The data obtained point to the advisability of the inclusion of hemosorption into a multiple modality treatment of patients with a persistent grand mal status and serial epileptic attacks. High circulating levels of immune complexes in the blood serum may be considered as indication for hemosorption.
