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2.
Biull Eksp Biol Med ; 93(5): 45-6, 1982 May.
Article in Russian | MEDLINE | ID: mdl-7093506

ABSTRACT

Experiments on mice have shown that severe mechanical trauma brings about phasic changes in the kinetics of hemopoietic stem cell migration. Within the first four days after the trauma the migration of stem cells gets intensified and returns to normal by day 8. This reaction is regarded to be a defence one, since it guarantees the function of the most important component of immunity, namely the organs where stem cells differentiate as T and B lymphocytes.


Subject(s)
Crush Syndrome/physiopathology , Hematopoietic Stem Cells/physiology , Shock, Traumatic/physiopathology , Animals , Bone Marrow Cells , Cell Movement/radiation effects , Colony-Forming Units Assay , Female , Hematopoietic Stem Cells/radiation effects , Kinetics , Mice , Mice, Inbred C57BL , Mice, Inbred CBA , Time Factors
16.
Biull Eksp Biol Med ; 80(11): 30-2, 1975 Nov.
Article in Russian | MEDLINE | ID: mdl-1218254

ABSTRACT

The authors studied the activity of acid phosphatase (AP), lactic dehydrogenase (LDH), aspartic and alanine-aminotranspherases (AST and ALT) in the serum of rats with intact and removed adrenal glands after a severe multifocal trauma induced according to Noble-Collip (300 rpt of the drum with the rotation speed of 37 rpt/min). Adrenalectomy showed practically no influence on the dynamics of the LDH and AP activity. An increase in the activity of the AST and especially of the ALT in the serum of adrenalectomized rats after the trauma was considerably less than in the animals with the intact adrenal glands.


Subject(s)
Adrenal Glands/physiopathology , Shock, Traumatic/physiopathology , Acid Phosphatase/blood , Animals , Aspartate Aminotransferases/blood , L-Lactate Dehydrogenase/blood , Male , Rats , Shock, Traumatic/blood , Shock, Traumatic/enzymology
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