Subject(s)
Arthrogryposis/physiopathology , Arthrogryposis/diagnosis , Arthrogryposis/therapy , Humans , Infant , Male , Physical Therapy Modalities , PrognosisABSTRACT
AIM: Study of the clinical presentation and laboratory data of type 1 diabetes in the Eastern Province of Saudi Arabia. METHODS: The medical records of all affected children during the period 1986-1997 were reviewed for the analysis of clinical and laboratory data. RESULTS: Type 1 diabetes was diagnosed in 46 children, 27 girls and 19 boys, with a mean age at diagnosis of 9.0 yr. The mean duration of symptoms prior to diagnosis was 12.5 d. Depressed consciousness occurred in 10.8% of the patients (none was comatose) and ketoacidosis in 77%. There was no episode of increased intracranial pressure during treatment, nor was there any death. There was a correlation between the central nervous system depression and the degree of hyperglycemia, and also with the severity of acidosis. CONCLUSIONS: Although more than three quarters of patients with type 1 diabetes had ketoacidosis on presentation, none was comatose or developed clinical cerebral edema during treatment. The presentation of type 1 diabetes in children from Saudi Arabia seems to differ from reports from developed countries.
ABSTRACT
OBJECTIVE: Study of the incidence of childhood type 1 diabetes in the Eastern Province of Saudi Arabia. METHODS: Analysis included all children eligible for care in our hospital who had type 1 diabetes diagnosed before their 15th birthday between 1986 and 1997. RESULTS: A total of 46 children (27 girls and 19 boys) were identified, with a median age at diagnosis of 10.3 yr. The overall age-adjusted incidence rate was 12.3 x 10(5)/yr; it was 9.9 x 10(5)/yr for males and 14.8 x 10(5)/yr for females. The number of patients increased significantly (relative risk of 46) over the study period (p=0.01), more significantly in females (p=0.007) and in the 10-14 year age group (p=0.01). CONCLUSIONS: The incidence of type 1 diabetes increased markedly over the past 12 years, mainly in females and children over 10 years of age. The data confirm the need to develop a national registry and the need for further epidemiological research.
Subject(s)
Diabetes Mellitus, Type 1/epidemiology , Adolescent , Child , Child, Preschool , Female , Humans , Incidence , Infant , Male , Retrospective Studies , Saudi Arabia/epidemiologyABSTRACT
OBJECTIVE: To determine the incidence of antenatal and intrapartum maternal and fetal complications of gestational diabetes mellitus (GDM) and compare them with pre-gestational diabetes mellitus (pre-GDM) and non-diabetic pregnancies in our population. STUDY DESIGN: Nine-hundred and seventy-two women with gestational diabetes mellitus and 71 women with pre-gestational diabetes mellitus, and their offspring (delivered in our hospital between January 1991 and April 1994) were studied. Maternal and fetal prenatal and intrapartum complications were analyzed. RESULTS: The incidence of GDM was 9.8%. The maternal complications included higher incidences of cesarean section and perineal lacerations in GDM and pre-GDM patients than in the non-diabetic pregnancies, and higher rates of macrosomia and hypoglycemic episodes in their offspring. CONCLUSION: The incidence of maternal, fetal and neonatal complications in GDM is similar to pre-GDM patients and their offspring. Both GDM and pre-GDM pregnancies and the offspring should, therefore, be monitored and managed identically.
Subject(s)
Diabetes Complications , Diabetes, Gestational/complications , Fetal Diseases/etiology , Pregnancy Outcome , Adult , Cesarean Section , Diabetes, Gestational/epidemiology , Female , Humans , Parity , Pregnancy , PrevalenceABSTRACT
We report the results of a five-year study of cord blood screening for congenital hypothyroidism in a genetically homegenous population in the Eastern Province of Saudi Arabia. The prevalence of congenital hypothyroidism was 1/5061 and is compared to other reports. The prevalence of dyshormonogenesis was 1/7592, higher than in other reports.
ABSTRACT
Eighteen children with infective endocarditis were detected over seven years. Fever, gastrointestinal and chest symptoms were striking features. Anaemia, elevated leukocyte count and sedimentation rate were constant laboratory findings. Strep. Viridans and Staph. Aureus were the commonest organisms isolated. We concluded that rheumatic and congenital heart disease are equally important in predisposition to infective endocarditis.
Subject(s)
Endocarditis, Bacterial/microbiology , Academic Medical Centers , Adolescent , Causality , Child , Child, Preschool , Endocarditis, Bacterial/epidemiology , Endocarditis, Bacterial/physiopathology , Female , Humans , Lebanon/epidemiology , Male , Survival RateABSTRACT
Twelve sick neonates, ten of whom were prematures, were found to have transient primary hypothyroidism. Two months after cessation of treatment all those followed were found to be clinically and biochemically euthyroid. The possible etiologic factors in the pathogenesis of transient hypothyroidism of the sick prematures are discussed. Iodine deficiency is probably an important precipitating cause.
