Subject(s)
Chagas Disease , Tachycardia, Ventricular , Humans , Magnetic Resonance Imaging , Endocardium/diagnostic imaging , Endocardium/surgery , Chagas Disease/complications , Chagas Disease/diagnostic imaging , Chagas Disease/surgery , Magnetic Resonance Spectroscopy , Tachycardia, Ventricular/diagnostic imaging , Tachycardia, Ventricular/surgerySubject(s)
Chagas Cardiomyopathy , Chagas Disease , Tachycardia, Ventricular , Humans , Latin America , Chagas Disease/complications , Tachycardia, Ventricular/etiology , Tachycardia, Ventricular/radiotherapy , Tachycardia, Ventricular/surgery , Chagas Cardiomyopathy/radiotherapy , Chagas Cardiomyopathy/surgeryABSTRACT
OBJECTIVE: Hypoparathyroidism is characterized by parathyroid hormone deficiency and hypocalcemia. It has been demonstrated that these patients may also present psychiatric symptoms and decrease of quality of life. The aims of this study were to evaluate the presence of psychopathological symptoms in a cohort of patients with hypoparathyroidism and compare to a control group. SUBJECTS AND METHODS: Patients were submitted to a cross-sectional Symptom Checklist-90-R (SCL-90-R) questionnaire that evaluates psychopathological symptoms by means of the Global Severity Index (GSI), Positive Symptoms Total (PST) and Positive Symptom Distress Index (PSDI). A score based in the positive symptoms was calculated (T-score). The test group was composed of patients with hypoparathyroidism, and control by thyroidectomized patients without hypoparathyroidism. A correlation between the presence of psychological symptoms and clinical features was analyzed. RESULTS: The study included 57 patients with a mean age of 51.1 ± 16.4 years; 20 as a control and 37, test group. There were no differences between groups regarding gender, mean age and age at diagnose. Hypoparathyroidism patients presented higher GSI index than the control group (p = 0.038). Mean T-score of the test group was as elevated as 58.2 ± 5.3 (reference range < 55). No correlation of the number of psychological symptoms to clinical and laboratorial parameters was observed. CONCLUSION: Patients with hypoparathyroidism attending our outpatient clinics presented an increase in the number of self-report of psychological symptoms when compared with a control group. However, no correlation with hypocalcemia and clinical parameters was observed. Future studies are necessary to evaluated if the absence of PTH play a role on it.
Subject(s)
Hypoparathyroidism/psychology , Quality of Life , Case-Control Studies , Cohort Studies , Cross-Sectional Studies , Female , Humans , Hypoparathyroidism/surgery , Male , Middle Aged , Self Report , Surveys and QuestionnairesABSTRACT
ABSTRACT Objective: Hypoparathyroidism is characterized by parathyroid hormone deficiency and hypocalcemia. It has been demonstrated that these patients may also present psychiatric symptoms and decrease of quality of life. The aims of this study were to evaluate the presence of psychopathological symptoms in a cohort of patients with hypoparathyroidism and compare to a control group. Subjects and methods: Patients were submitted to a cross-sectional Symptom Checklist-90-R (SCL-90-R) questionnaire that evaluates psychopathological symptoms by means of the Global Severity Index (GSI), Positive Symptoms Total (PST) and Positive Symptom Distress Index (PSDI). A score based in the positive symptoms was calculated (T-score). The test group was composed of patients with hypoparathyroidism, and control by thyroidectomized patients without hypoparathyroidism. A correlation between the presence of psychological symptoms and clinical features was analyzed. Results: The study included 57 patients with a mean age of 51.1 ± 16.4 years; 20 as a control and 37, test group. There were no differences between groups regarding gender, mean age and age at diagnose. Hypoparathyroidism patients presented higher GSI index than the control group (p = 0.038). Mean T-score of the test group was as elevated as 58.2 ± 5.3 (reference range < 55). No correlation of the number of psychological symptoms to clinical and laboratorial parameters was observed. Conclusion: Patients with hypoparathyroidism attending our outpatient clinics presented an increase in the number of self-report of psychological symptoms when compared with a control group. However, no correlation with hypocalcemia and clinical parameters was observed. Future studies are necessary to evaluated if the absence of PTH play a role on it.
Subject(s)
Humans , Male , Female , Middle Aged , Quality of Life , Hypoparathyroidism/psychology , Case-Control Studies , Cross-Sectional Studies , Surveys and Questionnaires , Cohort Studies , Self Report , Hypoparathyroidism/surgeryABSTRACT
BACKGROUND: Capsular contracture is a common occurrence in plastic surgery, with a prevalence varying from 0.5 percent up to 30 percent. Although the standard treatment is capsulectomy, alternative treatments have been studied, such as the use of leukotriene inhibitors. These drugs have recently been evaluated in the prophylaxis of contracture. The authors aimed to assess the efficacy of montelukast (Singulair) in the prevention of capsular contracture in patients undergoing mammaplasty with textured silicone prostheses. METHODS: The authors followed 82 patients (164 breasts) for a minimum of 2 years. Of these, 37 were administered montelukast. RESULTS: The number of affected patients and the severity were higher among the 45 patients who did not use montelukast. CONCLUSION: The prophylactic use of Singulair was, in this sample, shown to be effective in helping to reduce the incidence of capsular contracture. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.
