[Possible approaches to increase longevity of experimental animals.]

A statistically significant difference in the cumulative survival of Wistar rats born in different seasons has been shown: animals born in late November - early December had an average lifespan by 24,8% longer, a minimum lifespan by 14,3% longer, and a maximum lifespan by 20,7% longer in comparison with animals born in April. The geroprotective effect of the technique of thymus tissue transplantation into the immune privileged anterior chamber of the eye in animals born both in November and April has been shown.

[Study of the accidental thymus involution during the formation of hierarchic communities by a novel physical method for recording the social stress].

A novel method for recording the aggressive behavior in newly formed hierarchic communities has been developed. A temporal and age-related dynamics of the accidental thymus involution in mammals has been studied.

[The increase of the average and maximum span of life by the allogenic thymic cells transplantation in the animals' anterior chamber of eye].

The effect of the allogenic thymic tissue transplantation in the immune-privileged anterior chamber of eye to the life expectancy of the recipient depending on its age was investigated. The thymic tissue transplantation from the young animals to the old ones leads to a significant increase in both the average and maximum life span of the recipient.