ABSTRACT
We designed a new complex drug with antiallergic effect containing, in addition to the main component loratadine, a phytocomplex for an extra therapeutic effect. A collection of plants with sedative activity is chosen and the optimal agent for extraction of bioactive compounds (40% ethanol) and optimal degree of plant fragmentation are determined. Chemical composition of the sedative tea is evaluated by reverse phase HPLC. The marker components of the species are detected: xanthohumol and isoxanthohumol - Humulus lupulus cone components, Mentha piperita rosmarinic acid, and scutellareine, Menyanthes trifolia element - quercetin-3-rutinoside, and caffeic acid. Standardization of the species by the absolute graduation method in conversion to quercetin-3-rutinoside is suggested.
Subject(s)
Histamine H1 Antagonists/isolation & purification , Humulus/chemistry , Mentha piperita/chemistry , Phytochemicals/isolation & purification , Suppositories/chemical synthesis , Apigenin/chemistry , Apigenin/isolation & purification , Caffeic Acids/chemistry , Caffeic Acids/isolation & purification , Chromatography, High Pressure Liquid , Cinnamates/chemistry , Cinnamates/isolation & purification , Depsides/chemistry , Depsides/isolation & purification , Ethanol/chemistry , Flavonoids/chemistry , Flavonoids/isolation & purification , Histamine H1 Antagonists/chemistry , Histamine H1 Antagonists/standards , Humans , Phytochemicals/chemistry , Phytochemicals/standards , Plant Extracts/chemistry , Propiophenones/chemistry , Propiophenones/isolation & purification , Rutin/chemistry , Rutin/isolation & purification , Solvents/chemistry , Xanthones/chemistry , Xanthones/isolation & purification , Rosmarinic AcidABSTRACT
Causes of recurrences and unsatisfactory results of rectocele surgical treatment (except wound suppuration after surgery) were analyzed. It was concluded that prolapse of rectal mucosa and (or) severe muscular atrophy of the pelvic fundus uncorrected during transvaginal correction of rectocele are the main causes. It is recommended to resect mucosal excess by a traditional or A. Longo's method in the former case and to use synthetic net in the latter. This brings about favorable results in these patients.
Subject(s)
Postoperative Complications/surgery , Rectocele/surgery , Adult , Aged , Defecation , Female , Humans , Intestinal Mucosa/surgery , Middle Aged , Muscular Atrophy/complications , Muscular Atrophy/surgery , Patient Satisfaction , Postoperative Complications/physiopathology , Prolapse , Rectocele/complications , Rectocele/physiopathology , Rectum/surgery , Recurrence , Surgical Mesh , Treatment OutcomeSubject(s)
Hemorrhoids/surgery , Intestine, Large/surgery , Surgical Wound Infection/prevention & control , Aerosols , Anti-Bacterial Agents/therapeutic use , Bacteria/drug effects , Bacteria/isolation & purification , Drug Evaluation , Hemorrhoids/complications , Hemorrhoids/microbiology , Humans , Intestine, Large/microbiology , Ointments/therapeutic use , Povidone-Iodine/therapeutic use , Rectum/microbiology , Surgical Wound Infection/microbiologyABSTRACT
The authors analyze 36 cases of operative procedures for surgical complications of ulcer disease in children and juveniles. Perforation of ulcer was noted in 30 cases, bleeding--in 4 cases, combination of penetration of ulcer into the pancreas head with bleeding--in one case, in the other case--perforation of gastric ulcer with bleeding. Emphasis is laid on the severity of complications and in relation with it a question arises of early diagnosis and treatment of ulcer disease in children and juveniles.
