ABSTRACT
Magnesium and oxidative status were investigated in young volunteers exposed to chronic stress (political intolerance, awareness of potential military attacks, permanent stand-by duty and reduced holidays more than 10 years) or subchronic stress consisting of everyday mortal danger in military actions lasting more than 3 months. Significant decreases in plasma ionized Mg2+, total Mg and ionized Ca2+ concentrations were found in both groups. Similarly, both study groups exhibited oxidative stress as assessed by increased plasma superoxide anions and malondialdehyde and modified antioxidant defense. There were no significant differences between the two stress groups. A negative correlation between magnesium balance and oxidative stress was observed suggesting that the same etiological factor (chronic stress) initiate decreases in both free and total magnesium concentrations and simultaneously increase oxidative stress intensity. These findings support the need for magnesium supplementation with antioxidant vitamins for people living in conditions of chronic stress.
Subject(s)
Magnesium/metabolism , Oxidative Stress , Stress, Psychological/metabolism , Adolescent , Adult , Calcium/blood , Case-Control Studies , Humans , Magnesium/blood , Male , Malondialdehyde/blood , Sulfhydryl Compounds/blood , Superoxide Dismutase/blood , Superoxides/bloodABSTRACT
Owing to the asphyxia of the child weighing 4460 g, the delivery of a 33-year-old secundipara was completed by vacuum extraction. In the course of delivery the patient was bleeding very little. Following the delivery she complained of the numbness of the left hand and headache, she was pale, restless, and all in a cold sweat. The blood pressure was unmeasurable and the peripheral pulse could not be felt. Reanimation started at once. After a short improvement the patient's condition was getting worse. For suspected intra-abdominal hemorrhage, abdominal hysterectomy was applied. The operation revealed the incomplete rupture of the uterus. The patient died in the course of the operation. Venous air embolism was diagnosed only during obduction and was most probably the consequence of air aspiration through the split uterine veins.
