ABSTRACT
BACKGROUND: Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders largely affecting women of reproductive age group. OBJECTIVES: This study aimed to understand the Indian public health-care systems' preparedness in addressing PCOS. MATERIALS AND METHODS: A multicentric rapid assessment cross-sectional study was undertaken among 173 health-care providers serving across various public health-care facilities in India. This study was a component of a larger task force study that aimed to estimate the community-based prevalence of PCOS in India. Information on PCOS cases reported that knowledge about PCOS diagnosis, management practices, availability of diagnostic facilities, and drugs was explored. RESULTS: Irregular menstrual cycle was the most commonly reported PCOS symptom. Most of the health-care providers (HCPs) lacked correct knowledge about diagnostic criteria and investigation needed for the diagnosis of PCOS. Diagnostic facilities and drugs were inadequate. However, some facilities had access to investigations through public-private partnerships. Awareness programs on PCOS in the community were negligible, and PCOS cases were not documented. Training HCPs on PCOS along with the availability of specialists and strengthening diagnostic facilities were some major demands from the HCPs. CONCLUSION: Results suggest the need for training HCPs, strengthening infrastructure with good referral linkages, and adequate supply of drugs to help improve PCOS management at public health-care facilities in India. There is a need to develop national technical and operational guidelines to address PCOS using a multidisciplinary approach across all levels of care. Creating demand for services and advocating healthy lifestyles through community awareness can help early diagnosis and prevention of complications.
Subject(s)
Health Knowledge, Attitudes, Practice , Health Personnel , Polycystic Ovary Syndrome , Humans , Polycystic Ovary Syndrome/therapy , Polycystic Ovary Syndrome/epidemiology , Female , India/epidemiology , Cross-Sectional Studies , Health Personnel/education , Adult , MaleABSTRACT
Successive extracts of whole plant of Actiniopteris radiata screened for its therapeutic potential as an antiallergic and antistress agent in asthma using specific in vivo animal models. Only ethanol extract (AREE) at a higher dose of 100 mg/kg i.p significantly (p < 0.05) decreased milk induced eosinophilia by 16.20 ± 2.235 when compared with control group while even lower doses of 50 mg/kg, i.p exhibited significant inhibition (P < 0.05) of leukocytosis induced by milk in mice. Other extracts like petroleum ether, ethyl acetate and methanol unable to exhibit that significant potential. Results obtained thus validate the traditional claim of the Actiniopteris radiata utilization in different aspect of asthma due to presence of various polar secondary metabolites in ethanol extract.
Subject(s)
Anti-Allergic Agents/pharmacology , Anti-Asthmatic Agents/pharmacology , Eosinophilia/prevention & control , Ferns , Leukocytosis/prevention & control , Plant Extracts/pharmacology , Animals , Anti-Allergic Agents/administration & dosage , Anti-Allergic Agents/isolation & purification , Anti-Allergic Agents/toxicity , Anti-Asthmatic Agents/administration & dosage , Anti-Asthmatic Agents/isolation & purification , Anti-Asthmatic Agents/toxicity , Disease Models, Animal , Dose-Response Relationship, Drug , Eosinophilia/chemically induced , Ethanol/chemistry , Female , Ferns/chemistry , Injections, Intraperitoneal , Lethal Dose 50 , Leukocytosis/chemically induced , Mice , Milk , Plant Extracts/administration & dosage , Plant Extracts/isolation & purification , Plant Extracts/toxicity , Plants, Medicinal , Rats , Rats, Wistar , Solvents/chemistryABSTRACT
Distinction between true and pseudo trail in lumbo-sacral region is important since treatment and prognosis are different. Fewer than 40 cases have been reported in literature. The authors report a case of true tail in a neonate, a rare event.