1.
Fitoterapia
; 78(2): 120-4, 2007 Feb.
Article
in English
| MEDLINE
| ID: mdl-17169502
ABSTRACT
The Celastrus oil, extracted from seeds of Celastrus paniculatus tested at 2 dose levels (1 and 1.5 g/kg), exhibited significant anxiolytic activity and did not produce tolerance. The non-sedative nature and reversal of buspirone induced behaviour (in open field exploration) point to the serotonergic mechanism underlying the anxiolysis, inspiring further research.