Hyperbaric Oxygen Therapy-A Novel Treatment Modality in Oral Submucous Fibrosis: A Review.

Oral submucous fibrosis (OSMF) is a chronic, debilitating disease characterized by juxta epithelial fibrosis of the oral cavity and regarded as a potentially malignant disorder. Numerous treatment modalities ranging from various drugs to behavioral therapy have been tried with inconsistent results with varying degrees of success reflecting low predictability, requiring further evaluation and standardization. Novel treatment modality such as Hyperbaric oxygen therapy (HBOT) involves inhalation of 100% oxygen at increased atmospheric pressure usually ranging between 2.0 and 2.5 atmospheres for periods between 60 and 120 min. HBOT which can increase oxygen tension and delivery to oxygen-deficient tissue, is a supplementary therapy to improve hypoxic environment of OSMF and also possesses potent anti-inflammatory properties. This article enlightens on possible beneficial effects of HBOT in the management of OSMF at cellular and molecular level.

Malignant peripheral nerve sheath tumor: A rarity.

Malignant peripheral nerve sheath tumor (MPNST) of the mandible is an uncommon tumor that develops either from a preexisting neurofibroma or de novo. MPNSTs are sarcomas that originate from peripheral nerves or from cells associated with the nerve sheath, such as Schwann cells, perineural cells or from fibroblasts. Because MPNSTs can arise from multiple cell types, the overall appearance can vary greatly from one case to the next. A case of MPNST of the right side of the mandible in a 23-year-old female is reported.

Dimensional accuracy and details of the panoramic cross-sectional tomographic images: an in vitro study.

INTRODUCTION: Transversal slicing system (TSS) of Planmeca PM 2002 CC is a tomographic technique which enables us to take cross-sectional views of jaws. Tomographic imaging modalities are commonly applied to acquire cross-sectional images of the jaws for preimplant assessment of bone. Among the available tomographic imaging modalities, panoramic radiography is the most accessible imaging system. MATERIALS AND METHODS: Study was conducted using 25 mandibles, out of these five were used for linear dimensional accuracy measurement and the rest 20 were utilized to study the details within the mandible. Study was aimed to evaluate dimensional stability in the images using different parameters, such as determination of direction of slice, determination of horizontal and vertical magnification, angular distortion, three dimensional distortion and determination of details. RESULTS: For the direction of slice and for determination of horizontal and vertical magnification change in + 5º to - 5º was in acceptable limit. In determination of details, it was found that there was great discrepancy in readings given by nonradiologist which offset the mean value which was attributed to lack of training for interpretation of the observers. CONCLUSION: 99% of the readings were in the clinically acceptable limits. CLINICAL SIGNIFICANCE: The easy availability, use of routine equipment, the low cost, low radiation dose for cross-sectional radiography make the TSS most preferred modality.

Comparative evaluation of resistance failure in nonprecious metal-ceramic restoration at the incisal edge with varying thickness under different application of load: an in vitro study.

OBJECTIVE: To determine the resistance failure value of nonprecious metal-ceramic restorations at the incisal edge with varying thickness under different application of load. MATERIALS AND METHODS: An Ivorian central incisor was prepared to receive metal-ceramic crown, which was further duplicated, invested, casted and 72 metal dies were fabricated in Co-Cr alloy. Metal dies were relieved with die spacer, lubricated and wax patterns were prepared for metal copings, which were further invested and casted and 72 metal copings were fabricated. The ceramic materials were used for the study viz. Vita/VMK, IPSd SIGN, and superporcelain. Ceramic built-up was carried out according to manufacturer instructions. Incisal ceramic built-up was carried out with increasing thickness from 2.00 to 2.5 and 3.00 mm. RESULTS: A total of 72 samples, prepared for the study, were divided into two groups, i.e. group I (36 samples) and group II (36 samples), as per the direction of application of load. The samples were mounted on acrylic block (6 samples/block). A total 12 acrylic blocks were prepared. All the samples were tested using universal testing machine (MTS/USA). The load was applied with crosshead speed of 5 mm/min. CONCLUSION: Fracture resistance was found to be highest for the 2.00 mm and lowest for 3.00 mm incisal ceramic thickness samples regardless of the ceramic material in both groups. There was a gradual decrease in fracture resistance as the incisal ceramic thickness increased from 2.00 to 3.00 mm in all samples. Fracture resistance was marginally higher for incisal ceramic build-up of 3 mm thickness on group II metal copings than on group I copings. Fracture resistance was highest for IPSd SIGN followed by that of Vita/VMK-95 and superporcelain. CLINICAL SIGNIFICANCE: A 3.00 mm incisal ceramic thickness offered greater fracture resistance in comparison to lower values of incisal thickness; IPSd SIGN offered greatest fracture resistance followed by that of Vita/VMK-95 and superporcelain.