ABSTRACT
Objective: We aimed to evaluate the effectiveness of functional mandibular advancer (FMA) in treating growing patients with Class II malocclusion. Methods: Electronic searches were conducted in MEDLINE (via PubMed), Cochrane Library, Web of Science, Scopus, Embase, and Lilacs from 1945 to 30th November 2021. Studies were selected based on the following inclusion criteria: human studies, Class II growing patient treated with FMA, untreated control group or a comparable group treated with another fixed functional appliance, pre- and post-treatment lateral cephalograms/magnetic resonance imaging/cone-beam computed tomography, randomized clinical trials, prospective studies, and retrospective studies. Data extraction of the included articles was independently performed independently by two authors. The risk of bias was assessed using the ROBINS-I tool. Meta-analysis was performed using the inverse generic model. Results: Seven articles met the criteria and were included in the systematic review and three articles were included in the meta-analysis. Three studies had at low risk of bias and four studies had a moderate risk of bias. All articles reported anterior positioning of the mandible along with an increase in mandibular length. The meta-analysis results indicated a negligible difference between FMA and other functional appliances for the parameters SNA [0.11, 95% confidence interval (CI) of -1.07 and 1.29] and ANB (-1.00, 95% CI of -1.34 and -0.65). The evidence was limited for soft tissue changes. Conclusion: Class II correction with FMA involved a combination of skeletal and dentoalveolar changes and was similar to other fixed functional appliances.
ABSTRACT
Solitary plasmacytoma of the skull is very rare, and only a few cases have been reported in the literature. It remains controversial whether solitary plasmacytoma of the skull is essentially identical with solitary plasmacytoma of bone or not. Solitary plasmacytoma of bone including solitary plasmacytoma of the skull is characterized by a radiologically solitary bone lesion, neoplastic plasma cells in the biopsy specimen, fewer than 5% plasma cells in bone marrow, <2.0 g/dl monoclonal protein in the serum when present and negative urine test for Bence Jones protein (monoclonal light chain). We report one case of a 70-year-old woman who referred to our hospital because of a progressive left parietal swelling. On clinical examination, a painless large soft mass in the right parietal region was observed. Computed tomography revealed an extra-axial mass in the in the left frontoparietal region. The lesion was totally excised despite the bleeding tendency. Histology disclosed the presence of a plasmacytoma. On follow-up examination, 7 months later no tumor recurrence or evidence of multiple myeloma was detected.
